{"title":"Corneoscleral plaque brachytherapy using 'BARC I-125 Ocu-Prosta seeds' in the management of iridociliary melanoma.","authors":"Ujjwal Prakash Jha, Subina Narang, Varsha Jindal","doi":"10.1136/bcr-2023-255721","DOIUrl":null,"url":null,"abstract":"<p><p>We present the case of a woman in her late 40s who presented with an iris lesion extending to the ciliary body and mature white cataract with a visual acuity of perception of light in her right eye. The tumour was managed with Bhabha Atomic Research Centre Iodine-125 (BARC I-125) Ocu-Prosta seeds plaque therapy with the amniotic membrane buffer technique. No corneal complications or secondary glaucoma were seen over a 6-month follow-up, and a reduction in tumour size was observed on MRI. Ten months post corneoscleral plaque brachytherapy (PB), the patient underwent phacoemulsification in the same eye and achieved a best corrected visual acuity of 20/40. This case highlights the use of cost-effective indigenous I-125 Ocu-Prosta seeds with amniotic membrane in the successful management of iridociliary melanoma, which has not been reported so far.</p>","PeriodicalId":9080,"journal":{"name":"BMJ Case Reports","volume":"18 5","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMJ Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/bcr-2023-255721","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
We present the case of a woman in her late 40s who presented with an iris lesion extending to the ciliary body and mature white cataract with a visual acuity of perception of light in her right eye. The tumour was managed with Bhabha Atomic Research Centre Iodine-125 (BARC I-125) Ocu-Prosta seeds plaque therapy with the amniotic membrane buffer technique. No corneal complications or secondary glaucoma were seen over a 6-month follow-up, and a reduction in tumour size was observed on MRI. Ten months post corneoscleral plaque brachytherapy (PB), the patient underwent phacoemulsification in the same eye and achieved a best corrected visual acuity of 20/40. This case highlights the use of cost-effective indigenous I-125 Ocu-Prosta seeds with amniotic membrane in the successful management of iridociliary melanoma, which has not been reported so far.
期刊介绍:
BMJ Case Reports is an important educational resource offering a high volume of cases in all disciplines so that healthcare professionals, researchers and others can easily find clinically important information on common and rare conditions. All articles are peer reviewed and copy edited before publication. BMJ Case Reports is not an edition or supplement of the BMJ.