Shoulder Injury Related to Vaccine Administration (SIRVA) Following COVID-19 Vaccination: Correlating MRI Findings with Patient Demographics.

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Tomography Pub Date : 2025-05-02 DOI:10.3390/tomography11050053

Naser Obeidat, Ruba Khasawneh, Ahmad Alrawashdeh, Ali M Abdel Kareem, Mohammad K Al-Na'asan, Mohammad Alkhatatba, Suhaib Bani Essa

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引用次数: 0

Abstract

Objectives: Shoulder injury related to vaccine administration (SIRVA), previously observed with influenza vaccines, has gained clinical significance with widespread COVID-19 vaccination. However, few studies correlate vaccine types and demographic factors with the MRI findings of SIRVA. This study aimed to evaluate MRI findings of SIRVA following COVID-19 vaccination and assess associations with vaccine type and patient characteristics.

Methods: A retrospective cohort study was conducted on 35 patients with new-onset shoulder complaints within six weeks of COVID-19 vaccination between May 2021 and May 2022. MRI findings suggestive of SIRVA were reviewed, including subacromial bursitis, rotator cuff tears, and adhesive capsulitis. Demographic data, vaccine type, clinical symptoms, and treatments were collected. Follow-up interviews (1-30 September 2024) assessed symptom persistence and vaccine hesitancy. Descriptive statistics and Chi-square tests were used to explore associations.

Results: Of the 35 patients (mean age 53.6 ± 9.0 years; 54.3% female), subacromial bursitis was the most common MRI finding (89.5%), followed by tendonitis (47.4%) and adhesive capsulitis (36.8%). Tendonitis correlated with older age (p = 0.024) and AstraZeneca vaccination (p = 0.033). Subacromial bursitis was linked to female sex (p = 0.013) and higher BMI (p = 0.023). Adhesive capsulitis was associated with receiving the Sinopharm vaccine (p = 0.029). Persistent symptoms (22.9%) were more common in younger patients, women, and those with right-sided injections.

Conclusions: SIRVA following COVID-19 vaccination showed different MRI patterns associated with female sex, higher BMI, and vaccine type. Awareness of these patterns may expedite recognition of COVID-19-associated SIRVA in routine practice.

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COVID-19疫苗接种后与疫苗管理（SIRVA）相关的肩伤：MRI结果与患者人口统计学的相关性

目的：之前在流感疫苗中观察到的与疫苗给药相关的肩伤（SIRVA），随着COVID-19疫苗的广泛接种获得了临床意义。然而，很少有研究将疫苗类型和人口统计学因素与SIRVA的MRI结果联系起来。本研究旨在评估COVID-19疫苗接种后SIRVA的MRI表现，并评估与疫苗类型和患者特征的关系。方法：对2021年5月至2022年5月期间接种COVID-19疫苗后6周内新发肩部疾病的35例患者进行回顾性队列研究。我们回顾了提示SIRVA的MRI表现，包括肩峰下滑囊炎、肩袖撕裂和粘连性囊炎。收集了人口统计数据、疫苗类型、临床症状和治疗方法。随访访谈（2024年9月1日至30日）评估了症状持续性和疫苗犹豫。使用描述性统计和卡方检验来探讨相关性。结果：35例患者(平均年龄53.6±9.0岁；54.3%女性)，肩峰下滑囊炎是最常见的MRI表现（89.5%），其次是肌腱炎（47.4%）和粘连性囊炎（36.8%）。肌腱炎与年龄较大（p = 0.024）和阿斯利康疫苗接种相关（p = 0.033）。肩峰下滑囊炎与女性（p = 0.013）和较高的身体质量指数（p = 0.023）有关。胶囊炎与接种国药疫苗相关（p = 0.029）。持续性症状（22.9%）在年轻患者、女性和右侧注射患者中更为常见。结论：COVID-19疫苗接种后SIRVA表现出与女性、高BMI和疫苗类型相关的不同MRI模式。认识到这些模式可以在日常实践中加快对covid -19相关SIRVA的识别。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tomography Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

2.70

自引率

10.50%

发文量

222

期刊介绍： TomographyTM publishes basic (technical and pre-clinical) and clinical scientific articles which involve the advancement of imaging technologies. Tomography encompasses studies that use single or multiple imaging modalities including for example CT, US, PET, SPECT, MR and hyperpolarization technologies, as well as optical modalities (i.e. bioluminescence, photoacoustic, endomicroscopy, fiber optic imaging and optical computed tomography) in basic sciences, engineering, preclinical and clinical medicine. Tomography also welcomes studies involving exploration and refinement of contrast mechanisms and image-derived metrics within and across modalities toward the development of novel imaging probes for image-based feedback and intervention. The use of imaging in biology and medicine provides unparalleled opportunities to noninvasively interrogate tissues to obtain real-time dynamic and quantitative information required for diagnosis and response to interventions and to follow evolving pathological conditions. As multi-modal studies and the complexities of imaging technologies themselves are ever increasing to provide advanced information to scientists and clinicians. Tomography provides a unique publication venue allowing investigators the opportunity to more precisely communicate integrated findings related to the diverse and heterogeneous features associated with underlying anatomical, physiological, functional, metabolic and molecular genetic activities of normal and diseased tissue. Thus Tomography publishes peer-reviewed articles which involve the broad use of imaging of any tissue and disease type including both preclinical and clinical investigations. In addition, hardware/software along with chemical and molecular probe advances are welcome as they are deemed to significantly contribute towards the long-term goal of improving the overall impact of imaging on scientific and clinical discovery.