The Incidence and Risk Factors for Medical Adhesive-Related Skin Injury in Cancer Patients in China: A Systematic Review and Meta-Analysis.

Abstract

To explore the incidence and risk factors for medical adhesive-related skin injury (MARSI) in cancer patients in China, and to provide a basic framework for approaches designed to reduce the occurrence of MARSI and improve the management of its risk factors. PubMed, Web of Science, The Cochrane Library, EmBase, CNKI, VIP, Wanfang, and CBM were searched from database inception to October 2024. The Agency for Healthcare Research and Quality and the Newcastle-Ottawa Scale were used to assess the quality of the included studies, and a random-effects model with Stata 15.0 software was utilized for calculating the pooled incidence and risk factor for MARSI in cancer patients. A total of 18 studies were included, with 11,393 patients. Meta-analysis showed that the pooled incidence of MARSI in Chinese cancer patients was 24%. In subgroup analyses, dermatitis demonstrated the highest incidence rate (10%). MARSI history, allergy history, dressing type (3M), puncture site (upper arm), gender (female), BMI > 25 kg/m², moist skin, and age (≥ 50 years) were risk factors for MARSI in cancer patients. The incidence of MARSI in Chinese cancer patients is high, and MARSI history, allergy history, dressing type (3M), puncture site, gender (female), BMI > 25 kg/m², moist skin, and age (≥ 50 years) were risk factors for the occurrence of MARSI in Chinese cancer patients, suggesting that early identification and protection of high-risk patients, and timely targeted preventive measures are important to reduce the incidence of MARSI in cancer patients.