A rare large vessels involvement in a patient with a clinical diagnosis of Granulomatosis with polyangiitis: A case report.

Abstract

A previously healthy 22-year-old female presented with complaints of fatigue, joints pain, headache, fever and night sweats for several months. She also reported a reddish painful left eye and a rash on her legs two months ago. On examination, her blood pressure was elevated at 160/100 mm/hg and her lower limb pulses were hardly palpable. On investigation, she had anterior and intermediate uveitis, nasal septal ulcer, proteinuria, positive C-ANCA and a computed tomography angiography showed multiple abdominal aortic aneurysms and occlusion of both the left common carotid artery and the right superficial femoral artery. Lymph node biopsy showed necrotizing granulomatous inflammation. The patient was diagnosed with granulomatosis with polyangiitis with large vessels involvement which is a rare finding.