Untested, unlicensed, unregulated: prescribing and oversight issues in physician-assisted dying/suicide.

IF 2 4区医学 Q3 HEALTH CARE SCIENCES & SERVICES

BMJ Supportive & Palliative Care Pub Date : 2025-05-25 DOI:10.1136/spcare-2025-005612

Sheila Hollins, Suzy Lishman, Georgina Starling, Ruslan Zinchenko

引用次数: 0

Abstract

Current lethal combinations and doses of drugs used in physician-assisted dying/suicide are untested, unlicensed and unregulated, with little pharmacological understanding of efficacy and safety at high doses. Despite this, the proposed legislation would bypass regulatory safeguards, licensing, adverse event reporting and coroner referral. In any other area of medicine, such practices would be unacceptable. Before legalisation, we recommend that a formal, prospective clinical trial should be undertaken to establish the safety, efficacy and acceptability of different practices in end-of-life care including any use of lethal drug combinations. We also suggest that prescribing, licensing and monitoring gaps should be addressed.

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未经检验、无执照、无管制：医生协助死亡/自杀的处方和监督问题。

目前在医生协助死亡/自杀中使用的致命药物组合和剂量未经检验、未经许可和不受管制，对高剂量时的疗效和安全性缺乏药理学认识。尽管如此，拟议的立法将绕过监管保障、发牌、不良事件报告和死因裁判官转介。在任何其他医学领域，这种做法都是不可接受的。在药物合法化之前，我们建议进行正式的前瞻性临床试验，以确定临终关怀中不同做法的安全性、有效性和可接受性，包括任何致命药物组合的使用。我们还建议解决处方、许可和监测方面的差距。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMJ Supportive & Palliative Care Medicine-Medicine (miscellaneous)

CiteScore

4.60

自引率

7.40%

发文量

170

期刊介绍： Published quarterly in print and continuously online, BMJ Supportive & Palliative Care aims to connect many disciplines and specialties throughout the world by providing high quality, clinically relevant research, reviews, comment, information and news of international importance. We hold an inclusive view of supportive and palliative care research and we are able to call on expertise to critique the whole range of methodologies within the subject, including those working in transitional research, clinical trials, epidemiology, behavioural sciences, ethics and health service research. Articles with relevance to clinical practice and clinical service development will be considered for publication. In an international context, many different categories of clinician and healthcare workers do clinical work associated with palliative medicine, specialist or generalist palliative care, supportive care, psychosocial-oncology and end of life care. We wish to engage many specialties, not only those traditionally associated with supportive and palliative care. We hope to extend the readership to doctors, nurses, other healthcare workers and researchers in medical and surgical specialties, including but not limited to cardiology, gastroenterology, geriatrics, neurology, oncology, paediatrics, primary care, psychiatry, psychology, renal medicine, respiratory medicine.