Oxcarbazepine Induced Rhabdomyolysis and Acute Kidney Injury: A Case Report.

Case Reports in Nephrology Pub Date : 2025-05-16 eCollection Date: 2025-01-01 DOI:10.1155/crin/4168888
Sara Yavuz Ileri, Nuray Can Usta
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引用次数: 0

Abstract

The cause of acute skeletal muscle damage, defined as rhabdomyolysis, is multifactorial. Medicines are prominent among the most important reasons. The clinical significance of rhabdomyolysis lies in the fact that it can cause acute kidney injury (AKI) in 10%-40% of patients. In this presented case, oxcarbazepine, which is a preferred drug in the treatment of epilepsy and also in neuropathic pain in clinical practice, triggered rhabdomyolysis and subsequently caused the development of AKI. Through this case report, we aimed to emphasize that some serious side effects should not be forgotten when prescribing drugs in clinical practice.

奥卡西平致横纹肌溶解和急性肾损伤1例报告。
急性骨骼肌损伤的原因,定义为横纹肌溶解,是多因素的。药物是最重要的原因之一。横纹肌溶解的临床意义在于10%-40%的患者可引起急性肾损伤(AKI)。在本病例中,奥卡西平是治疗癫痫和临床神经性疼痛的首选药物,引发横纹肌溶解,随后导致AKI的发展。通过本病例报告,我们旨在强调在临床用药时,一些严重的副作用是不可忽视的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Case Reports in Nephrology
Case Reports in Nephrology Medicine-Nephrology
CiteScore
1.70
自引率
0.00%
发文量
32
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