Surgical interventions in Severe Osteoarthritis: Pros and Cons.

Journal of orthopaedics and sports medicine Pub Date : 2025-01-01 Epub Date: 2025-03-31 DOI:10.26502/josm.511500192
Andre Aabedi, Marcel P Fraix, Devendra K Agrawal
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Abstract

Severe osteoarthritis (OA) is a debilitating condition that often necessitates surgical intervention when conservative treatments fail. We carefully reviewed the literature on the pros and cons of surgical options for severe OA, focusing on total joint arthroplasty (TJA) and other surgical techniques. Total joint arthroplasty, including total knee arthroplasty (TKA) and total hip arthroplasty (THA), is the most established surgical option for severe OA, providing significant pain relief, functional restoration, and improved quality of life. The American College of Rheumatology and the American Association of Hip and Knee Surgeons recommend proceeding to TJA without delay in patients with symptomatic moderate-to-severe OA unresponsive to nonoperative therapy. Osteotomies and cartilage repair procedures are less commonly performed and have limited evidence supporting their long-term efficacy in reducing OA progression. Arthroscopic interventions, such as lavage and debridement, do not alter disease progression and are not recommended for routine treatment of OA. While TJA is highly effective, it is associated with risks such as postoperative complications, revisions, and reoperations. The cost-effectiveness of TJA is well-documented, making it a favorable option for managing end stage OA. However, patient selection is crucial, and factors such as age, comorbidities, and obesity must be considered to optimize outcomes. Total joint arthroplasty remains the gold standard for surgical management of severe OA, offering substantial benefits in pain relief and functional improvement. Other surgical options, such as osteotomies and arthroscopy, have limited roles and should be considered based on individual patient factors and disease severity. Evidence-based guidelines support the timely use of TJA to enhance patient outcomes and quality of life.

重度骨关节炎的手术干预:利弊。
严重骨关节炎(OA)是一种使人衰弱的疾病,当保守治疗失败时,通常需要手术干预。我们仔细回顾了关于严重OA手术选择的利弊的文献,重点是全关节置换术(TJA)和其他手术技术。全关节置换术,包括全膝关节置换术(TKA)和全髋关节置换术(THA),是治疗严重骨关节炎最成熟的手术选择,可显著缓解疼痛,恢复功能,提高生活质量。美国风湿病学会和美国髋关节和膝关节外科医师协会建议对非手术治疗无反应的症状性中重度OA患者立即进行TJA治疗。截骨术和软骨修复术不太常见,并且支持其在减少OA进展方面的长期疗效的证据有限。关节镜干预,如灌洗和清创,不改变疾病进展,不推荐作为OA的常规治疗。虽然TJA是非常有效的,但它与术后并发症、翻修和再手术等风险相关。TJA的成本效益是有案可查的,使其成为管理末期OA的有利选择。然而,患者的选择是至关重要的,必须考虑年龄、合并症和肥胖等因素,以优化结果。全关节置换术仍然是严重OA手术治疗的金标准,在疼痛缓解和功能改善方面提供了实质性的好处。其他手术选择,如截骨术和关节镜检查,作用有限,应根据个体患者因素和疾病严重程度进行考虑。循证指南支持及时使用TJA以提高患者预后和生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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