Doxycycline en prévention des infections sexuellement transmissibles, pratiques d’utilisation : revue narrative de la littérature.

IF 0.3 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Sante Publique Pub Date : 2025-01-01 DOI:10.3917/spub.251.0119

Liliane Mouche, Sibylle de Germay, Justine Perino, Charles Cazanave

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引用次数: 0

Abstract

Introduction: The off-label use of doxycycline to prevent certain sexually transmitted infections (STIs), outside controlled research environments, has been occurring for several years.

Purpose of the study: The objective of this study was to describe the off-label use of doxycycline as a preventive treatment for STIs by conducting a review of the literature, including analysis of a social network.

Results: In total, 11 eligible references were identified, comprising 9 letters and 2 original articles. One press article and six Reddit® discussions were also selected. Most doxycycline users identified in this study were men who have sex with men, with numerous partners and without using condoms. Doxycycline was mainly prescribed by a doctor, but some users obtain the medication in its veterinary form via the internet. HIV PrEP was identified as a factor leading to the decision to take doxycycline. While most users expressed confidence in its efficacy, some expressed reservations due to its inability to provide comprehensive protection against all STIs, and due to the occurrence of side effects.

Conclusion: The increase in self-medication with doxycycline for STI prevention necessitates enhanced monitoring, addressing both disease transmission risks and potential adverse drug reactions.

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阿霉素在性传播感染预防中的应用：文献叙事综述。

多年来，在受控研究环境之外，超说明书使用强力霉素来预防某些性传播感染（STIs）的情况一直存在。研究目的：本研究的目的是通过对文献的回顾，包括对社会网络的分析，来描述强力霉素作为性传播感染的预防性治疗的超说明书使用。结果：共纳入符合条件的参考文献11篇，其中书信9篇，原创文章2篇。一篇新闻文章和六个Reddit®讨论也被选中。在这项研究中，大多数强力霉素使用者是与男性发生性关系的男性，他们有很多伴侣，而且没有使用避孕套。多西环素主要由医生开处方，但一些使用者通过互联网获得兽医形式的药物。HIV PrEP被确定为导致决定服用强力霉素的一个因素。虽然大多数使用者对其功效表示信任，但有些人表示保留，因为它不能对所有性传播感染提供全面保护，并且由于出现了副作用。结论：多西环素自我用药预防性传播感染的人数增加，需要加强监测，同时解决疾病传播风险和潜在的药物不良反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sante Publique PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

0.40

自引率

33.30%

发文量

252

审稿时长

>12 weeks

期刊介绍： La revue Santé Publique s’adresse à l’ensemble des acteurs de santé publique qu’ils soient décideurs, professionnels de santé, acteurs de terrain, chercheurs, enseignants ou formateurs, etc. Elle publie des travaux de recherche, des évaluations, des analyses d’action, des réflexions sur des interventions de santé, des opinions, relevant des champs de la santé publique et de l’analyse des services de soins, des sciences sociales et de l’action sociale. Santé publique est une revue à comité de lecture, multidisciplinaire et généraliste, qui publie sur l’ensemble des thèmes de la santé publique parmi lesquels : accès et recours aux soins, déterminants et inégalités sociales de santé, prévention, éducation pour la santé, promotion de la santé, organisation des soins, environnement, formation des professionnels de santé, nutrition, politiques de santé, pratiques professionnelles, qualité des soins, gestion des risques sanitaires, représentation et santé perçue, santé scolaire, santé et travail, systèmes de santé, systèmes d’information, veille sanitaire, déterminants de la consommation de soins, organisation et économie des différents secteurs de production de soins (hôpital, médicament, etc.), évaluation médico-économique d’activités de soins ou de prévention et de programmes de santé, planification des ressources, politiques de régulation et de financement, etc