Prevalence of cardiovascular and renal comorbidities among patients with type 2 diabetes routinely treated in the primary care setting in Greece: An epidemiological study (the RECARDIA study)

IF 2.9 3区医学 Q3 ENDOCRINOLOGY & METABOLISM

Journal of diabetes and its complications Pub Date : 2025-05-21 DOI:10.1016/j.jdiacomp.2025.109087

Nikolaos Papanas , Vasileios Tsimihodimos , Niki Katsiki , John Doupis , Emmanouil Pagkalos , Nikos Nikas , Nikos Papakonstantopoulos , George Karpouzos , Nikolaos Tentolouris

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引用次数: 0

Abstract

Aims

This study aimed to generate real-world data on the prevalence of cardiovascular disease (CVD), including atherosclerotic CVD (ASCVD) and heart failure (HF), as well as chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM) routinely treated in Greece.

Methods

This was a non-interventional, epidemiological, multicentre, cross-sectional and retrospective chart review study of T2DM patients attending a routine clinical visit at 198 outpatient primary care settings across Greece from November 2020 to February 2022.

Results

Among 2000 enrolled T2DM outpatients, the prevalence of ASCVD was 20.40 % (95 % confidence interval [CI]: 18.67 %–22.25 %), of HF 8.03 % (95 % CI: 6.67 %–9.63 %), and of CKD 49.55 % (95 % CI: 47.36 %–51.74 %). Hypertension was correlated with increased risk of ASCVD, HF or CKD, dyslipidaemia with ASCVD and CKD, obesity solely with HF, and smoking with ASCVD. Patients over 65 years were at higher risk of ASCVD, HF or CKD, whereas those with T2DM for ≥10 years had a higher risk of ASCVD or HF. Finally, males were more likely to have ASCVD

Conclusions

The present study confirms the high prevalence of CVD and CKD among Greek T2DM patients managed in primary care, that potentially qualify for new antidiabetic treatments with cardiovascular or renal benefits.

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希腊初级保健机构常规治疗的2型糖尿病患者心血管和肾脏合并症患病率：一项流行病学研究（RECARDIA研究）

目的：本研究旨在获得在希腊常规治疗的2型糖尿病（T2DM）患者心血管疾病（CVD）患病率的真实数据，包括动脉粥样硬化性CVD （ASCVD）和心力衰竭（HF），以及慢性肾脏疾病（CKD）。方法：这是一项非干预性、流行病学、多中心、横断面和回顾性的图表回顾研究，研究对象是2020年11月至2022年2月在希腊198个门诊初级保健机构进行常规临床就诊的T2DM患者。结果2000例T2DM门诊患者中，ASCVD患病率为20.40%(95%可信区间[CI]: 18.67% - 22.25%)， HF患病率为8.03% (95% CI: 6.67% - 9.63%)， CKD患病率为49.55% （95% CI: 47.36% - 51.74%）。高血压与ASCVD、HF或CKD、合并ASCVD和CKD的血脂异常、合并HF的肥胖和合并ASCVD的吸烟的风险增加相关。65岁以上的患者发生ASCVD、HF或CKD的风险较高，而T2DM≥10年的患者发生ASCVD或HF的风险较高。最后，男性更有可能患有ascvd。结论：目前的研究证实，在希腊接受初级保健治疗的T2DM患者中，CVD和CKD的患病率较高，这些患者可能有资格接受具有心血管或肾脏益处的新型降糖治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of diabetes and its complications 医学-内分泌学与代谢

CiteScore

5.90

自引率

3.30%

发文量

153

审稿时长

16 days

期刊介绍： Journal of Diabetes and Its Complications (JDC) is a journal for health care practitioners and researchers, that publishes original research about the pathogenesis, diagnosis and management of diabetes mellitus and its complications. JDC also publishes articles on physiological and molecular aspects of glucose homeostasis. The primary purpose of JDC is to act as a source of information usable by diabetes practitioners and researchers to increase their knowledge about mechanisms of diabetes and complications development, and promote better management of people with diabetes who are at risk for those complications. Manuscripts submitted to JDC can report any aspect of basic, translational or clinical research as well as epidemiology. Topics can range broadly from early prediabetes to late-stage complicated diabetes. Topics relevant to basic/translational reports include pancreatic islet dysfunction and insulin resistance, altered adipose tissue function in diabetes, altered neuronal control of glucose homeostasis and mechanisms of drug action. Topics relevant to diabetic complications include diabetic retinopathy, neuropathy and nephropathy; peripheral vascular disease and coronary heart disease; gastrointestinal disorders, renal failure and impotence; and hypertension and hyperlipidemia.