The correlation between serum albumin, exercise endurance, and pulmonary complications after lobectomy.

Abstract

Background: The aim of the article is to explore the relationship between serum albumin, exercise endurance, and pulmonary complications after lobectomy.

Methods: Overall, 166 lung cancer patients who were treated in our hospital from January 2020 to June 2023 were selected to analyze the incidence of postoperative pulmonary complications and the differences in clinical data between patients with and without pulmonary complications. Logistic regression equations were used to analyze the influencing factors of postoperative pulmonary complications.

Results: There were 46 patients with postoperative pulmonary complications, incidence rate was 27.71%; Among the 46 patients, eight had two or more complications. The age of patients with pulmonary complications was 69.29±6.65 years old, which was higher than that of patients without pulmonary complications (P<0.05). The proportions of surgical time ≥4 hours, intraoperative blood loss ≥50 mL, and preoperative albumin <35 g/L in patients with pulmonary complications were 58.70%, 65.22% and 76.09%, respectively, which were significantly higher than those in patients without pulmonary complications (P<0.05). Patients with pulmonary complications had peak expiratory flow rate (PEF), peak oxygen uptake as a percentage of expected value (VO2%P), kilogram oxygen uptake (VO2/kg), anaerobic threshold (AT), oxygen pulse as percentage of expected value (O2pulse%P), respiratory rate (BF), and 6-Minute Walking Test (6-MWT), which were 291.10±43.34 L/min, 55.54±12.21%, 16.21±4.32 mL, 44.45±10.02%, 71.18±15.56 L, 26.68±6.67 times and 410.04±45.54 m, which were significantly lower than patients without pulmonary complications (P>0.05). Logistic regression analysis showed that age, surgical time, preoperative albumin, VO2% P, and 6-MWT were the influencing factors for postoperative pulmonary complications (P<0.05).

Conclusions: Serum albumin, cardiopulmonary motility indicators, and 6MWT are associated with the occurrence of pulmonary complications after lobectomy, and the occurrence of pulmonary complications is influenced by patient age and surgical time.