Potentially inappropriate medication use and comorbidity in association with quality of life in community-dwelling older people: a cross-sectional study in Iran.

IF 2.6 Q2 MEDICINE, GENERAL & INTERNAL
Maryam Shirdozham, Awat Feizi, Majid Rahimi
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Abstract

Background: Multimorbidity, polypharmacy, and potentially inappropriate medication use in older adults are prevalent and affect their quality of life. This study investigates the interrelationship between potentially inappropriate medication use, comorbidity, and quality of life among older adults in Iran.

Methods: This cross-sectional study was conducted on 500 older adults in Isfahan City, Iran. The Beers Criteria for Potentially Inappropriate Medication Use in Older Adults, a health-related quality-of-life questionnaire for older adults, and the Charlson Comorbidity Index were used to gather data.

Results: Our findings related to older adults living in the Isfahan community showed that the prevalence of PIM was 61.6%, and the most common drug category was painkillers. The average quality of life score was (0.86 ± 0.08), and the worst category was related to sleep status. The average score of the CCI was 3.63 ± 1.40, with the most frequent diseases being hyperlipidemia, hypertension, and diabetes. After adjusting for confounding variables, a negative relationship between CCI (B = -0.009 [SE = 0.0027], P < 0.001) and PIM (B = -0.03 [SE = 0.007], P < 0.001) with quality of life was observed.

Conclusion: Potentially inappropriate medication uses and comorbidities are high in our older population, and these variables are negatively associated with quality of life in this population. There are few family physicians trained in geriatrics in Iran. Policymakers should pay attention to these issues.

在伊朗的一项横断面研究中,居住在社区的老年人的潜在不适当的药物使用和合并症与生活质量有关。
背景:老年人的多病、多药和潜在的不适当用药普遍存在,并影响他们的生活质量。本研究调查了伊朗老年人潜在的不适当用药、合并症和生活质量之间的相互关系。方法:对伊朗伊斯法罕市的500名老年人进行了横断面研究。使用Beers老年人潜在不当用药标准、老年人健康相关生活质量问卷和Charlson合并症指数收集数据。结果:居住在伊斯法罕社区的老年人PIM患病率为61.6%,最常见的药物类别为止痛药。平均生活质量评分为(0.86±0.08)分,最差类别与睡眠状态有关。CCI的平均得分为3.63±1.40,高脂血症、高血压和糖尿病是最常见的疾病。在调整混杂变量后,CCI (B = -0.009 [SE = 0.0027])与P呈负相关。结论:老年人群中潜在的不当用药和合并症发生率很高,这些变量与该人群的生活质量呈负相关。在伊朗,接受过老年病学培训的家庭医生很少。政策制定者应该关注这些问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
4.40
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