Acne management in Norway: general practitioner and dermatologist prescriptions (2012-2019), a nationwide overview.

IF 2.5 Q2 PRIMARY HEALTH CARE
BJGP Open Pub Date : 2025-05-20 DOI:10.3399/BJGPO.2024.0211
Cathrine S Christiansen, Sigurd Høye, Morten Lindbaek, Jon Anders Halvorsen, Louise Emilsson
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引用次数: 0

Abstract

Background: Acne is common and associated with negative psychosocial health and risk of permanent skin alterations. General practitioners (GPs) prescribe the main portion of antibiotics used for acne. Increased isotretinoin prescription by GPs can potentially reduce overall antibiotic use, but prescription practice andtrends are unknown.

Aim: We aimed to examine acne treatment in Norway and quantify prescription and initiation of isotretinoin and tetracyclines.

Design & setting: Data was collected from the Norwegian Prescription Database and the National GP Claims Register.

Method: All patients aged 12 - 39 who received an acne diagnosis or were prescribed acne medication in Norway 2012 - 2019 were included. Linear regression was used to explore time trends.

Results: In total, 316,075 patients were included (63% female). Yearly prevalence of systemic treatment increased from 1.9 in 2012 to 2.4% in 2019; isotretinoin increased by+123%, tetracyclines by+4% as measured in defined daily doses. Topical treatment increased by+13% as measured by number of prescriptions. GP prescription of tetracyclines decreased - 11%, however, courses had a mean duration of 160 days, which is longer than the recommended 90, and only 26% had a co-occurring topical treatment prescription. GPs initiated 5% of isotretinoin courses in 2012, vs. 10% in 2019, and 19% (N=1,339) of GPs ever initiated isotretinoin during the study period.

Conclusion: GPs reduced their prescription of tetracyclines, still our data shows potential for further improvements in prescribing practice. Increased isotretinoin prescription by GPs may lead to reduced antibiotic use and better treatment regimens for moderate-severe acne.

挪威的痤疮管理:全科医生和皮肤科医生处方(2012-2019),全国概况。
背景:痤疮是常见的,与负面的社会心理健康和永久性皮肤改变的风险有关。全科医生(全科医生)处方抗生素的主要部分用于痤疮。全科医生增加异维甲酸处方可能会减少抗生素的总体使用,但处方实践和趋势尚不清楚。目的:我们旨在研究挪威的痤疮治疗,并量化异维甲酸和四环素的处方和起始。设计与设置:数据收集自挪威处方数据库和国家全科医生索赔登记册。方法:纳入2012 - 2019年挪威所有12 - 39岁接受痤疮诊断或处方痤疮药物的患者。采用线性回归分析时间趋势。结果:共纳入316,075例患者(63%为女性)。全身治疗的年患病率从2012年的1.9%上升到2019年的2.4%;按规定的每日剂量测量,异维甲酸增加了+123%,四环素增加了+4%。按处方数量计算,局部治疗增加了+13%。全科医生的四环素处方减少了11%,然而,疗程的平均持续时间为160天,比推荐的90天要长,只有26%的人同时服用局部治疗处方。2012年,全科医生启动了5%的异维a酸课程,2019年为10%,在研究期间,19% (N= 1339)的全科医生启动了异维a酸课程。结论:全科医生减少了四环素类药物的处方,但我们的数据显示在处方实践中有进一步改进的潜力。全科医生增加异维甲酸处方可能会减少抗生素的使用,并改善中重度痤疮的治疗方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BJGP Open
BJGP Open Medicine-Family Practice
CiteScore
5.00
自引率
0.00%
发文量
181
审稿时长
22 weeks
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