Study protocol for a parallel-group, randomized controlled trial of enhanced cue exposure therapy for negative emotional eating

IF 1.9 3区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Wai Sze Chan, Wing Yee Cheng
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引用次数: 0

Abstract

Background

Negative emotional eating (NEE) refers to overeating in response to negative emotions. The efficacy of cue exposure therapy (CET) for treating NEE has not been evaluated in a full-scale randomized controlled trial (RCT). Moreover, previously tested CET did not fully utilize theory-informed intervention strategies. Hence, an enhanced version of CET (E-CET) is here developed and evaluated. E-CET will integrate theory-informed intervention strategies including (1) exposures that incorporate food cues, emotional cues, and idiosyncratic contextual cues, (2) homework exposures, and, (3) explicit instructions to violate the conditioned stimulus-unconditioned stimulus (CS-US) expectancies maintaining NEE. E-CET is hypothesized to promote greater reductions in NEE than an active control, behavioral lifestyle intervention (BLI), and its efficacy will be mediated by the reduction in the believability of CS-US expectancies.

Methods

This is a parallel-group RCT. One-hundred-and-thirty-eight participants with recurring NEE will be randomly assigned to E-CET or BLI, and attend six individual sessions. The primary outcome is the change in the emotional eating subscale score measured by the Dutch Eating Behavior Questionnaire at posttreatment, 3-month, and 12-month follow-up from baseline. Secondary and mechanistic outcomes include changes in NEE measured by ecological momentary assessments, caloric consumption, and the believability in CS-US expectancies.

Discussion

If shown to be efficacious, E-CET can be implemented to reduce NEE. This study will be the first experimental evaluation of the mediating effects of CS-US expectancy violation in the working of E-CET for NEE to inform developments of the theories on CET and NEE.
一项平行组随机对照试验的研究方案:强化线索暴露疗法治疗消极情绪进食
负面情绪进食(NEE)指的是对负面情绪的过度进食。提示暴露疗法(CET)治疗NEE的疗效尚未在一项全面的随机对照试验(RCT)中进行评估。此外,以前测试的CET并没有充分利用理论知情的干预策略。因此,在这里开发和评估了一个改进版的CET (E-CET)。E-CET将整合基于理论的干预策略,包括(1)包含食物线索、情绪线索和特殊情境线索的暴露,(2)家庭作业暴露,以及(3)违反条件刺激-非条件刺激(CS-US)预期的明确指示,以维持NEE。假设E-CET比主动对照行为生活方式干预(BLI)更能促进NEE的减少,其效果将通过CS-US预期可信度的降低来调节。方法采用平行组随机对照试验。138名反复出现NEE的参与者将被随机分配到E-CET或BLI,并参加6个单独的课程。主要结果是在治疗后、3个月和12个月的基线随访中,通过荷兰饮食行为问卷测量的情绪饮食亚量表得分的变化。次要和机械结果包括通过生态瞬时评估、热量消耗和CS-US预期的可信度测量的NEE变化。如果被证明是有效的,E-CET可以实施以减少新能源消耗。本研究将首次通过实验评估CS-US期望违反对新英语学习的中介作用,为新英语学习和新英语学习理论的发展提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.70
自引率
4.50%
发文量
281
审稿时长
44 days
期刊介绍: Contemporary Clinical Trials is an international peer reviewed journal that publishes manuscripts pertaining to all aspects of clinical trials, including, but not limited to, design, conduct, analysis, regulation and ethics. Manuscripts submitted should appeal to a readership drawn from disciplines including medicine, biostatistics, epidemiology, computer science, management science, behavioural science, pharmaceutical science, and bioethics. Full-length papers and short communications not exceeding 1,500 words, as well as systemic reviews of clinical trials and methodologies will be published. Perspectives/commentaries on current issues and the impact of clinical trials on the practice of medicine and health policy are also welcome.
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