{"title":"Correction: CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1‑529aa protein and regulating PRDX2 protein stability","authors":"Yu Zhang, Jiajia Jiang, Jiayin Zhang, Han Shen, Maoye Wang, Zhen Guo, Xueyan Zang, Hui Shi, Jiayan Gao, Hui Cai, Xinjian Fang, Hui Qian, Wenrong Xu, Xu Zhang","doi":"10.1186/s12943-025-02356-0","DOIUrl":null,"url":null,"abstract":"<p><b>Correction</b><b>: </b><b>Mol Cancer 20, 101 (2021)</b></p><p><b>https://doi.org/10.1186/s12943-021-01390-y</b></p><br/><p>Following the publication of the original article [1], the authors have identified two layout-related errors that occurred during the figure assembly or production process. In Figure 2d, the images for the MGC-803 cell invasion assay were inadvertently misplaced. In Additional file 1: Supplementary Figure 1e, the MGC-803 cell invasion assay images were also affected by a similar layout error. The incorrect and correct figure is provided below. The Supplementary Figure 1 has been updated in the Supplementary Information section of this correction note article.</p><p>Incorrect Figure 2:</p><figure><picture><source srcset=\"//media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12943-025-02356-0/MediaObjects/12943_2025_2356_Figa_HTML.png?as=webp\" type=\"image/webp\"/><img alt=\"figure a\" aria-describedby=\"Figa\" height=\"830\" loading=\"lazy\" src=\"//media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12943-025-02356-0/MediaObjects/12943_2025_2356_Figa_HTML.png\" width=\"685\"/></picture></figure><p>Correct Figure 2:</p><figure><picture><source srcset=\"//media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12943-025-02356-0/MediaObjects/12943_2025_2356_Figb_HTML.png?as=webp\" type=\"image/webp\"/><img alt=\"figure b\" aria-describedby=\"Figb\" height=\"783\" loading=\"lazy\" src=\"//media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12943-025-02356-0/MediaObjects/12943_2025_2356_Figb_HTML.png\" width=\"685\"/></picture></figure><ol data-track-component=\"outbound reference\" data-track-context=\"references section\"><li data-counter=\"1.\"><p>Zhang Y, Jiang J, Zhang J, et al. CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1-529aa protein and regulating PRDX2 protein stability. Mol Cancer. 2021;20:101. https://doi.org/10.1186/s12943-021-01390-y.</p><p>Article PubMed PubMed Central Google Scholar </p></li></ol><p>Download references<svg aria-hidden=\"true\" focusable=\"false\" height=\"16\" role=\"img\" width=\"16\"><use xlink:href=\"#icon-eds-i-download-medium\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"></use></svg></p><span>Author notes</span><ol><li><p>Yu Zhang and Jiajia Jiang contributed equally to this work.</p></li></ol><h3>Authors and Affiliations</h3><ol><li><p>Aoyang Cancer Institute, Affiliated Aoyang Hospital of Jiangsu University, Zhangjiagang, 215600, Jiangsu, China</p><p>Yu Zhang, Jiajia Jiang, Jiayin Zhang, Maoye Wang, Zhen Guo, Xueyan Zang, Hui Shi, Jiayan Gao, Hui Qian, Wenrong Xu & Xu Zhang</p></li><li><p>Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, Jiangsu, China</p><p>Yu Zhang, Jiajia Jiang, Jiayin Zhang, Han Shen, Maoye Wang, Zhen Guo, Xueyan Zang, Hui Shi, Hui Qian, Wenrong Xu & Xu Zhang</p></li><li><p>Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, 210009, Jiangsu, China</p><p>Yu Zhang, Han Shen & Xu Zhang</p></li><li><p>Department of Oncology, Lianyungang Hospital Affiliated To Jiangsu University, Lianyungang, 222000, Jiangsu, China</p><p>Hui Shi, Xinjian Fang & Xu Zhang</p></li><li><p>Key Laboratory of Molecular Diagnostics and Precision Medicine for Surgical Oncology in Gansu Province, Gansu Hospital of Jiangsu University, Lanzhou, 730000, Gansu, China</p><p>Hui Shi, Hui Cai & Xu Zhang</p></li></ol><span>Authors</span><ol><li><span>Yu Zhang</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Jiajia Jiang</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Jiayin Zhang</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Han Shen</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Maoye Wang</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Zhen Guo</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Xueyan Zang</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Hui Shi</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Jiayan Gao</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Hui Cai</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Xinjian Fang</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Hui Qian</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Wenrong Xu</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Xu Zhang</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li></ol><h3>Corresponding authors</h3><p>Correspondence to Wenrong Xu or Xu Zhang.</p><h3>12943_2025_2356_MOESM1_ESM.pdf</h3><p>Additional file 1: Figure S1. CircDIDO1 knockdown promotes GC cell proliferation, migration, and invasion in vitro. a) Efficiency of gene knockdown in GC cells by siRNAs was confirmed by qRT-PCR. b) Cell growth curve, c) colony formation, d) transwell migration, and e) matrigel invasion assays for control and circDIDO1 knockdown GC cells.</p><p><b>Open Access</b> This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. 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0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>\" width=\"57\"/><h3>Cite this article</h3><p>Zhang, Y., Jiang, J., Zhang, J. <i>et al.</i> Correction: CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1‑529aa protein and regulating PRDX2 protein stability. <i>Mol Cancer</i> <b>24</b>, 146 (2025). https://doi.org/10.1186/s12943-025-02356-0</p><p>Download citation<svg aria-hidden=\"true\" focusable=\"false\" height=\"16\" role=\"img\" width=\"16\"><use xlink:href=\"#icon-eds-i-download-medium\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"></use></svg></p><ul data-test=\"publication-history\"><li><p>Published<span>: </span><span><time datetime=\"2025-05-21\">21 May 2025</time></span></p></li><li><p>DOI</abbr><span>: </span><span>https://doi.org/10.1186/s12943-025-02356-0</span></p></li></ul><h3>Share this article</h3><p>Anyone you share the following link with will be able to read this content:</p><button data-track=\"click\" data-track-action=\"get shareable link\" data-track-external=\"\" data-track-label=\"button\" type=\"button\">Get shareable link</button><p>Sorry, a shareable link is not currently available for 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Abstract
Correction: Mol Cancer 20, 101 (2021)
https://doi.org/10.1186/s12943-021-01390-y
Following the publication of the original article [1], the authors have identified two layout-related errors that occurred during the figure assembly or production process. In Figure 2d, the images for the MGC-803 cell invasion assay were inadvertently misplaced. In Additional file 1: Supplementary Figure 1e, the MGC-803 cell invasion assay images were also affected by a similar layout error. The incorrect and correct figure is provided below. The Supplementary Figure 1 has been updated in the Supplementary Information section of this correction note article.
Incorrect Figure 2:
Correct Figure 2:
Zhang Y, Jiang J, Zhang J, et al. CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1-529aa protein and regulating PRDX2 protein stability. Mol Cancer. 2021;20:101. https://doi.org/10.1186/s12943-021-01390-y.
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Author notes
Yu Zhang and Jiajia Jiang contributed equally to this work.
Authors and Affiliations
Aoyang Cancer Institute, Affiliated Aoyang Hospital of Jiangsu University, Zhangjiagang, 215600, Jiangsu, China
Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, 210009, Jiangsu, China
Yu Zhang, Han Shen & Xu Zhang
Department of Oncology, Lianyungang Hospital Affiliated To Jiangsu University, Lianyungang, 222000, Jiangsu, China
Hui Shi, Xinjian Fang & Xu Zhang
Key Laboratory of Molecular Diagnostics and Precision Medicine for Surgical Oncology in Gansu Province, Gansu Hospital of Jiangsu University, Lanzhou, 730000, Gansu, China
Hui Shi, Hui Cai & Xu Zhang
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12943_2025_2356_MOESM1_ESM.pdf
Additional file 1: Figure S1. CircDIDO1 knockdown promotes GC cell proliferation, migration, and invasion in vitro. a) Efficiency of gene knockdown in GC cells by siRNAs was confirmed by qRT-PCR. b) Cell growth curve, c) colony formation, d) transwell migration, and e) matrigel invasion assays for control and circDIDO1 knockdown GC cells.
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Zhang, Y., Jiang, J., Zhang, J. et al. Correction: CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1‑529aa protein and regulating PRDX2 protein stability. Mol Cancer24, 146 (2025). https://doi.org/10.1186/s12943-025-02356-0
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