Sinonasal NK/T-cell lymphoma - imaging features overlap with non-neoplastic etiologies.

IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Emergency Radiology Pub Date : 2025-05-17 DOI:10.1007/s10140-025-02350-5

Sneh Brahmbhatt, Jeremiah Daniel, Amit Agarwal, Vivek Gupta, Alok A Bhatt

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引用次数: 0

Abstract

Purpose: The purpose of this retrospective study is to evaluate imaging features of sinonasal NK/T-cell lymphoma, potentially aiding early diagnosis and improving patient outcomes through timely biopsy evaluation and treatment.

Materials & methods: This study was designed as a retrospective review. Imaging characteristics in a total of 28 patients with histology confirmed sinonasal NK/T-cell lymphoma were evaluated by two radiologists. Demographic data and clinical features were extracted from the electronic medical record.

Results: Among 28 patients, 84.6% presented with nasal cavity involvement and 88.5% with an isoattenuating lesion on CT and 63.6% with T2 hypointensity on MRI. Notably, 57.7% showed osseous destruction and 27.3% had devascularized tissue, highlighting significant radiologic features that may overlap with non-neoplastic etiologies.

Conclusion: Sinonasal NK/T-cell lymphoma should be in the differential diagnosis in patients presenting with chronic sinonasal symptoms and imaging findings of tissue necrosis, osseous destruction, and adjacent fat infiltration. Imaging features overlap with entities such as aggressive fungal sinusitis and granulomatosis with polyangiitis.

查看原文本刊更多论文

鼻窦NK/ t细胞淋巴瘤的影像学特征与非肿瘤性病因重叠。

目的：本回顾性研究的目的是评估鼻窦NK/ t细胞淋巴瘤的影像学特征，通过及时的活检评估和治疗，可能有助于早期诊断和改善患者预后。材料与方法：本研究为回顾性研究。两名放射科医生对28例经组织学证实的鼻窦NK/ t细胞淋巴瘤患者的影像学特征进行了评估。从电子病历中提取人口统计数据和临床特征。结果：28例患者中，84.6%表现为鼻腔受累，88.5% CT表现为等衰减病灶，63.6% MRI表现为T2低密度。值得注意的是，57.7%表现为骨破坏，27.3%表现为组织断流，突出了可能与非肿瘤性病因重叠的重要放射学特征。结论：鼻窦NK/ t细胞淋巴瘤应作为慢性鼻窦症状和影像学表现为组织坏死、骨破坏和邻近脂肪浸润的患者的鉴别诊断。影像特征与侵袭性真菌性鼻窦炎和肉芽肿病合并多血管炎重叠。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Emergency Radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

4.60

自引率

4.50%

发文量

期刊介绍： To advance and improve the radiologic aspects of emergency careTo establish Emergency Radiology as an area of special interest in the field of diagnostic imagingTo improve methods of education in Emergency RadiologyTo provide, through formal meetings, a mechanism for presentation of scientific papers on various aspects of Emergency Radiology and continuing educationTo promote research in Emergency Radiology by clinical and basic science investigators, including residents and other traineesTo act as the resource body on Emergency Radiology for those interested in emergency patient care Members of the American Society of Emergency Radiology (ASER) receive the Emergency Radiology journal as a benefit of membership!