Diaphragm neurostimulation in mechanical ventilation: current status and future prospects.

Expert review of medical devices Pub Date : 2025-06-01 Epub Date: 2025-05-15 DOI:10.1080/17434440.2025.2504454
Elizabeth C Rohrs, Steven Reynolds, Martin Dres
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引用次数: 0

Abstract

Introduction: Diaphragm neurostimulation is a muscle stimulation technique that, through electrodes placed directly on or at the vicinity of the phrenic nerves, induces diaphragm contractions independently of the patient's cooperation. Recently, the technical development of temporary diaphragm neurostimulation devices has paved the way for a new era in the management of critically ill patients.

Areas covered: In this review, we describe the latest technical developments in diaphragm neurostimulation and its physiological effects. We searched MEDLINE of experimental and clinical studies in English language published from database inception until 31 October 2024. We also discuss the advances in terms of patients centered outcomes and the key areas for improvement. Lastly, we introduce possible future directions and the novel improvements in patient care.

Expert opinion: The research on diaphragm neurostimulation promise as an emerging intervention which addresses common complications associated with mechanical ventilation. Large-scale clinical trials are necessary to validate diaphragm neurostimulation efficacy and safety in humans, establish treatment protocols, and determine cost-effectiveness, all of which are essential for diaphragm neurostimulation to be widely accepted in clinical practice.

膈神经刺激在机械通气中的应用现状及展望。
简介:膈神经刺激是一种肌肉刺激技术,通过电极直接放置在膈神经上或膈神经附近,诱导膈肌收缩,而不需要患者的配合。最近,暂时性膈神经刺激装置的技术发展为危重病人的管理开辟了一个新时代。涵盖领域:本文综述了隔膜神经刺激的最新技术进展及其生理效应。我们检索了MEDLINE从数据库建立到2024年10月31日发表的英语实验和临床研究。我们还讨论了以患者为中心的结果方面的进展和需要改进的关键领域。最后,我们介绍了未来可能的方向和病人护理的新改进。专家意见:隔膜神经刺激的研究有望作为一种新兴的干预措施,解决与机械通气相关的常见并发症。为了验证横膈膜神经刺激在人体中的有效性和安全性,建立治疗方案,确定成本效益,大规模的临床试验是必要的,所有这些都是横膈膜神经刺激在临床实践中被广泛接受的必要条件。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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