Filipa Jácome, Beatriz Ribeiro, João Rocha-Neves, José F Teixeira, Marina Dias-Neto
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引用次数: 0
Abstract
Background: The early survival benefits of endovascular aneurysm repair (EVAR) appear to diminish over time, and late aneurysm-related mortality remains a significant concern. Our aim is to determine the rate of secondary interventions (SI) and assess compliance with post-EVAR surveillance.
Methods: This retrospective cohort study included consecutive patients who underwent elective EVAR between February 2009 and May 2019 at a tertiary center. The primary outcomes were freedom from SI and compliance with follow-up (imaging performed within a time interval of no more than 18 months). Secondary outcome was overall patient survival.
Results: A total of 214 patients underwent EVAR, with a median follow-up of 44 months. During this period, 42 SI were performed in 25 patients. Of all SI, 33.3% (14/42) were due to symptomatic complications. Freedom from SI was 96.3±1.3% at 30 days and 93.6±1.7%, 90.3±2.2% and 85.9±3.0 at 1, 3 and 5 years, respectively. Endoleaks were the main cause of SI after EVAR (N.=26), primarily type 1 and type 2. At 5 years, patient survival rates were similar (76.7±4.1% vs. 84.4±7.2%, P=0.386). Compliance with surveillance was 80.4±2.9% at 1 year, and 37.7±5.4% at 5 years.
Conclusions: SI after EVAR were frequent, with endoleaks being the leading cause and associated with cases of aneurysm sac rupture. Although compliance with surveillance decreases over longer follow-up periods, the impact of this trend on long-term outcomes after EVAR warrants further investigation.
背景:血管内动脉瘤修复(EVAR)的早期生存益处似乎随着时间的推移而减少,晚期动脉瘤相关死亡率仍然是一个值得关注的问题。我们的目的是确定二次干预(SI)的比率,并评估evar后监测的依从性。方法:本回顾性队列研究纳入了2009年2月至2019年5月在三级中心接受选择性EVAR的连续患者。主要结果是无SI和随访依从性(在不超过18个月的时间间隔内进行影像学检查)。次要终点是患者的总生存率。结果:共有214例患者接受了EVAR,中位随访时间为44个月。在此期间,25例患者进行了42例SI。在所有SI中,33.3%(14/42)是由症状性并发症引起的。30天的SI自由度为96.3±1.3%,1年、3年和5年分别为93.6±1.7%、90.3±2.2%和85.9±3.0。内漏是EVAR术后SI的主要原因(26例),以1型和2型为主。5年生存率相似(76.7±4.1% vs 84.4±7.2%,P=0.386)。监测依从性1年为80.4±2.9%,5年为37.7±5.4%。结论:EVAR术后SI发生率高,以腔内漏为主要原因,并与动脉瘤囊破裂有关。尽管随访时间越长,监测依从性越低,但这一趋势对EVAR后长期预后的影响值得进一步调查。