A deep learning-based approach to automated rib fracture detection and CWIS classification.

IF 2.3 3区 医学 Q3 ENGINEERING, BIOMEDICAL
Victoria Marting, Noor Borren, Max R van Diepen, Esther M M van Lieshout, Mathieu M E Wijffels, Theo van Walsum
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引用次数: 0

Abstract

Purpose: Trauma-induced rib fractures are a common injury. The number and characteristics of these fractures influence whether a patient is treated nonoperatively or surgically. Rib fractures are typically diagnosed using CT scans, yet 19.2-26.8% of fractures are still missed during assessment. Another challenge in managing rib fractures is the interobserver variability in their classification. Purpose of this study was to develop and assess an automated method that detects rib fractures in CT scans, and classifies them according to the Chest Wall Injury Society (CWIS) classification.

Methods: 198 CT scans were collected, of which 170 were used for training and internal validation, and 28 for external validation. Fractures and their classifications were manually annotated in each of the scans. A detection and classification network was trained for each of the three components of the CWIS classifications. In addition, a rib number labeling network was trained for obtaining the rib number of a fracture. Experiments were performed to assess the method performance.

Results: On the internal test set, the method achieved a detection sensitivity of 80%, at a precision of 87%, and an F1-score of 83%, with a mean number of FPPS (false positives per scan) of 1.11. Classification sensitivity varied, with the lowest being 25% for complex fractures and the highest being 97% for posterior fractures. The correct rib number was assigned to 94% of the detected fractures. The custom-trained nnU-Net correctly labeled 95.5% of all ribs and 98.4% of fractured ribs in 30 patients. The detection and classification performance on the external validation dataset was slightly better, with a fracture detection sensitivity of 84%, precision of 85%, F1-score of 84%, FPPS of 0.96 and 95% of the fractures were assigned the correct rib number.

Conclusion: The method developed is able to accurately detect and classify rib fractures in CT scans, there is room for improvement in the (rare and) underrepresented classes in the training set.

基于深度学习的肋骨骨折自动检测和CWIS分类方法。
目的:外伤性肋骨骨折是一种常见的损伤。这些骨折的数量和特征影响患者是采用非手术治疗还是手术治疗。肋骨骨折通常通过CT扫描诊断,但在评估过程中仍有19.2-26.8%的骨折被遗漏。治疗肋骨骨折的另一个挑战是其分类的观察者之间的差异。本研究的目的是开发和评估一种在CT扫描中检测肋骨骨折的自动化方法,并根据胸壁损伤协会(CWIS)的分类对其进行分类。方法:收集198张CT扫描,其中170张用于训练和内部验证,28张用于外部验证。在每次扫描中手工标注骨折及其分类。为CWIS分类的三个组成部分中的每一个都训练了一个检测和分类网络。此外,还训练了一个肋骨号标记网络来获取骨折的肋骨号。通过实验验证了该方法的性能。结果:在内部测试集上,该方法的检测灵敏度为80%,精度为87%,f1评分为83%,平均FPPS(每次扫描的假阳性)为1.11。分类敏感性各不相同,复杂骨折最低为25%,后侧骨折最高为97%。在检测到的骨折中,正确的肋骨号被分配到94%。在30例患者中,定制训练的nnU-Net正确标记了95.5%的肋骨和98.4%的骨折肋骨。在外部验证数据集上的检测和分类性能稍好,骨折检测灵敏度为84%,精度为85%,f1评分为84%,FPPS为0.96,95%的骨折被分配到正确的肋骨号。结论:该方法能够在CT扫描中准确地检测和分类肋骨骨折,在训练集中(罕见和)代表性不足的类别有改进的空间。
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来源期刊
International Journal of Computer Assisted Radiology and Surgery
International Journal of Computer Assisted Radiology and Surgery ENGINEERING, BIOMEDICAL-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
CiteScore
5.90
自引率
6.70%
发文量
243
审稿时长
6-12 weeks
期刊介绍: The International Journal for Computer Assisted Radiology and Surgery (IJCARS) is a peer-reviewed journal that provides a platform for closing the gap between medical and technical disciplines, and encourages interdisciplinary research and development activities in an international environment.
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