Derivation of Provisional Drinking Water Tolerance Values for Several PFAS Not Included in the Austrian Drinking Water Regulation.

Food risk assess Europe Pub Date : 2025-04-01 Epub Date: 2025-05-12 DOI:10.2903/fr.efsa.2025.FR-0057
Lukas Meusburger, Elke Rauscher-Gabernig, Karin Manner, Johann Steinwider
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Abstract

Per- and polyfluorinated alkyl substances (PFAS) comprise a wide range of industrial chemicals that are currently being evaluated worldwide for their toxic and bioaccumulative properties. Some of these chemicals are already subject to restrictions. The Austrian Drinking Water Regulation (Trinkwasserverordnung, BGBl. II Nr. 304/2001, consolidated version of 16.05.2024) sets a limit of 0.1 μg/L for the sum of 20 PFAS in drinking water from 12 January 2026 as prescribed by Directive (EU) 2020/2184 [1]. However, a large number of PFAS are not covered by this Directive. For some of these compounds, provisional drinking water tolerance values for both adults and infants have been derived in this work. Toxicological assessments and drinking water guideline values derived by other authorities as well as scientific studies were used for this purpose. These provisional tolerance values were compared with the occurrence data of Austrian drinking water and groundwater, as were the health-based guidance values (HBGVs) with the estimated exposure. The tolerance values for adults were not exceeded; however, some measurements for GenX were above the derived provisional tolerance values for infants. The estimated exposures based on the concentrations of PFAS in ground or drinking water did not exceed the HBGVs, yet for infants, the highest levels reached 45 % of the HBGV in the case of GenX. While no immediate health risks are to be anticipated, it is important to ensure that concentrations of PFAS do not increase further.

奥地利饮用水法规中未包括的几种PFAS的临时饮用水容许值的推导。
全氟和多氟烷基物质(PFAS)包括范围广泛的工业化学品,目前正在世界范围内对其毒性和生物蓄积性进行评估。其中一些化学品已经受到限制。奥地利饮用水条例(Trinkwasserverordnung, BGBl)。II Nr. 304/2001,合并版本16.05.2024)根据指令(EU) 2020/2184[1]的规定,从2026年1月12日起,饮用水中20种PFAS的总和限制为0.1 μg/L。然而,该指令并未涵盖大量PFAS。对于其中一些化合物,在这项工作中得出了成人和婴儿的临时饮用水耐受值。为此目的使用了其他当局得出的毒理学评估和饮用水指导值以及科学研究。将这些临时容忍值与奥地利饮用水和地下水的发生率数据以及基于健康的指导值(HBGVs)与估计暴露量进行了比较。未超过成人的耐受值;然而,GenX的一些测量值高于推导出的婴儿临时容限值。基于地面或饮用水中PFAS浓度的估计暴露量没有超过HBGV,但对于婴儿,GenX的最高水平达到HBGV的45%。虽然预计不会立即出现健康风险,但重要的是要确保全氟磺酸钠的浓度不会进一步增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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