Spatial analysis of risk areas of congenital anomalies in Brazil, 2012-2021.

IF 2.5 Q1 Multidisciplinary

Epidemiologia e Servicos de Saude Pub Date : 2025-05-09 eCollection Date: 2025-01-01 DOI:10.1590/S2237-96222025v34e20250240.en

Suzana de Souza, Clarissa Gutierrez Carvalho, Lavinia Schuler-Faccini

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Abstract

Objective: To identify areas at risk for congenital anomalies in Brazil, from 2012 to 2021.

Method: Time series analysis using data from the Live Birth Information System. Prevalence of anomalies in the period was calculated according to immediate geographic region. Spatial analysis was performed by calculating the Global and Local Moran index and spatial scanning, with calculation of Relative Risk (RR) and p-value, for the risk areas.

Results: Areas at higher risk for anomalies were identified in the Northeast, Southeast, and Southern regions. The Northeast region had a higher number of clusters (n=31) and higher prevalence of nervous system anomalies compared to the other regions (9.7/10,000 live births). The highest risk of anomalies compared to the other areas was found in the state of Paraíba (RR 2.4; p-value<0.001).

Conclusion: Disparities in the distribution of congenital anomalies were identified in Brazil, with risk areas in the Northeast, Southeast, and Southern regions.

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2012-2021年巴西先天性畸形风险区空间分析

目的：确定2012年至2021年巴西先天性异常风险地区。方法：利用活产信息系统数据进行时间序列分析。根据邻近地理区域计算该期间的异常发生率。通过计算全球和局部Moran指数和空间扫描进行空间分析，计算风险区域的相对风险（RR）和p值。结果：在东北、东南和南部地区确定了异常风险较高的地区。与其他地区相比，东北地区有更多的群集（n=31）和更高的神经系统异常患病率（9.7/10,000活产）。与其他地区相比，异常风险最高的是Paraíba (RR 2.4；结论：巴西先天性畸形的分布存在差异，风险区主要集中在东北部、东南部和南部地区。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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