Painful exercise for people with knee osteoarthritis: a randomised controlled feasibility trial.

IF 2.1 4区医学 Q1 REHABILITATION

Disability and Rehabilitation Pub Date : 2025-05-15 DOI:10.1080/09638288.2025.2504614

Adrian Ram, Alexandre Kovats, Anurag Pandit, Pramod Ram, Mitchell T Gibbs, John Booth, Jeanette M Thom, Matthew D Jones

{"title":"Painful exercise for people with knee osteoarthritis: a randomised controlled feasibility trial.","authors":"Adrian Ram, Alexandre Kovats, Anurag Pandit, Pramod Ram, Mitchell T Gibbs, John Booth, Jeanette M Thom, Matthew D Jones","doi":"10.1080/09638288.2025.2504614","DOIUrl":null,"url":null,"abstract":"Purpose: Determine the feasibility of painful exercise for people with knee osteoarthritis (KOA) to inform a future randomised controlled trial. Materials and methods: People with KOA were randomised into painful (INT) or non-painful (CON) exercise groups. Both groups performed supervised exercise twice per week for 6 weeks and received standardised education. Feasibility was assessed using participant recruitment and retention rates as well as exercise adherence and compliance. Secondary outcomes included pain, function, strength, pressure pain threshold, psychosocial measures, global impression of change, and adverse events.Results: Twenty participants (67.4 ± 8.9 years old; 18 females) were randomised and 18 completed the study. Feasibility was supported by satisfactory rates of recruitment (INT 89%, CON 89%) and retention (INT 91%, CON 100%) as well as exercise adherence (INT 91%, CON 92%) and compliance (INT 72%, CON 81%). Outcomes improved similarly between groups, except for strength which increased more in INT compared to CON (13.0 [0.2-25.9] kg). Four participants (3 INT, 1 CON) took analgesic medication for exercise-induced pain exacerbations. No other adverse events were reported.Conclusion: When combined with education, painful exercise is feasible for KOA. Future research comparing the effectiveness and safety of painful exercise in KOA is warranted.Registration: ACTRN12622001231730.","PeriodicalId":50575,"journal":{"name":"Disability and Rehabilitation","volume":" ","pages":"1-9"},"PeriodicalIF":2.1000,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Disability and Rehabilitation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/09638288.2025.2504614","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"REHABILITATION","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: Determine the feasibility of painful exercise for people with knee osteoarthritis (KOA) to inform a future randomised controlled trial. Materials and methods: People with KOA were randomised into painful (INT) or non-painful (CON) exercise groups. Both groups performed supervised exercise twice per week for 6 weeks and received standardised education. Feasibility was assessed using participant recruitment and retention rates as well as exercise adherence and compliance. Secondary outcomes included pain, function, strength, pressure pain threshold, psychosocial measures, global impression of change, and adverse events.

Results: Twenty participants (67.4 ± 8.9 years old; 18 females) were randomised and 18 completed the study. Feasibility was supported by satisfactory rates of recruitment (INT 89%, CON 89%) and retention (INT 91%, CON 100%) as well as exercise adherence (INT 91%, CON 92%) and compliance (INT 72%, CON 81%). Outcomes improved similarly between groups, except for strength which increased more in INT compared to CON (13.0 [0.2-25.9] kg). Four participants (3 INT, 1 CON) took analgesic medication for exercise-induced pain exacerbations. No other adverse events were reported.

Conclusion: When combined with education, painful exercise is feasible for KOA. Future research comparing the effectiveness and safety of painful exercise in KOA is warranted.

Registration: ACTRN12622001231730.

查看原文本刊更多论文

膝关节骨关节炎患者的疼痛运动：一项随机对照可行性试验。

目的：确定膝关节骨关节炎（KOA）患者疼痛运动的可行性，为未来的随机对照试验提供信息。材料和方法：将KOA患者随机分为疼痛（INT）组和非疼痛（CON）组。两组均进行督导运动，每周2次，持续6周，并接受标准化教育。可行性评估采用参与者招募率和保留率以及运动依从性和依从性。次要结局包括疼痛、功能、力量、压力痛阈、心理社会测量、整体变化印象和不良事件。结果：20例（67.4±8.9岁）；随机抽取18名女性，其中18名完成了研究。可行性由满意的招募率（INT 89%, CON 89%）和保留率（INT 91%, CON 100%）以及运动依从性（INT 91%, CON 92%）和依从性（INT 72%, CON 81%）来支持。结果在两组之间也有类似的改善，除了力量在INT组比CON组增加更多（13.0 [0.2-25.9]kg）。4名参与者（3名INT， 1名CON）服用止痛药治疗运动引起的疼痛加重。没有其他不良事件的报道。结论：疼痛运动与教育相结合治疗KOA是可行的。未来的研究比较疼痛运动在KOA中的有效性和安全性是必要的。注册:ACTRN12622001231730。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Disability and Rehabilitation 医学-康复医学

CiteScore

5.00

自引率

9.10%

发文量

415

审稿时长

3-6 weeks

期刊介绍： Disability and Rehabilitation along with Disability and Rehabilitation: Assistive Technology are international multidisciplinary journals which seek to encourage a better understanding of all aspects of disability and to promote rehabilitation science, practice and policy aspects of the rehabilitation process.