Yuhan Zhang , Yishu Wei , Yanshan Wang , Yunyu Xiao , COL Ret. Ronald K. Poropatich , Gretchen L. Haas , Yiye Zhang , Chunhua Weng , Jinze Liu , Lisa A. Brenner , James M. Bjork , Yifan Peng
{"title":"Machine learning applications related to suicide in military and Veterans: A scoping literature review","authors":"Yuhan Zhang , Yishu Wei , Yanshan Wang , Yunyu Xiao , COL Ret. Ronald K. Poropatich , Gretchen L. Haas , Yiye Zhang , Chunhua Weng , Jinze Liu , Lisa A. Brenner , James M. Bjork , Yifan Peng","doi":"10.1016/j.jbi.2025.104848","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>Suicide remains one of the main preventable causes of death among service members and veterans. Early detection and accurate prediction are essential components of effective suicide prevention strategies. Machine learning techniques have been explored in recent years with a specific focus on the assessment and prediction of multiple suicide-related outcomes, showing promising advancements. This study aims to assess and summarize current research and provides a comprehensive review regarding the application of machine learning techniques in assessing and predicting suicidal ideation, attempts, and mortality among members of military and veteran populations.</div></div><div><h3>Methods</h3><div>A keyword search using PubMed, IEEE, ACM, and Google Scholar was conducted, and the PRISMA protocol was adopted for relevant study selection. Peer-reviewed original research in English targeting the assessment or prediction of suicide-related outcomes among service members and veteran populations was included. 1,110 studies were retrieved, and 32 satisfied the inclusion criteria and were included.</div></div><div><h3>Results</h3><div>Thirty-two articles met the inclusion criteria. Despite these studies exhibiting significant variability in sample characteristics, data modalities, specific suicide-related outcomes, and the machine learning technologies employed, they consistently identified risk factors relevant to mental health issues such as depression, post-traumatic stress disorder (PTSD), suicidal ideation, prior attempts, physical health problems, and demographic characteristics. Machine learning models applied in this area have demonstrated reasonable predictive accuracy and have verified, on a large scale, risk factors previously detected by more manual analytic methods. Additional research gaps still exist. First, many studies have overlooked metrics that distinguish between false positives and negatives, such as positive predictive value and negative predictive value, which are crucial in the context of suicide prevention policies. Second, more dedicated approaches to handling survival and longitudinal data should be explored. Lastly, most studies focused on machine learning methods, with limited discussion of their connection to clinical rationales.</div></div><div><h3>Conclusion</h3><div>In sum, machine learning analyses have identified risk factors associated with suicide in military populations, which span a wide range of psychological, biological, and sociocultural factors, highlighting the complexities involved in assessing suicide risk among service members and veterans. Some differences were noted between males and females. The diversity of these factors also demonstrates that effective prevention strategies must be comprehensive and flexible.</div></div>","PeriodicalId":15263,"journal":{"name":"Journal of Biomedical Informatics","volume":"167 ","pages":"Article 104848"},"PeriodicalIF":4.0000,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biomedical Informatics","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1532046425000772","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
引用次数: 0
Abstract
Objective
Suicide remains one of the main preventable causes of death among service members and veterans. Early detection and accurate prediction are essential components of effective suicide prevention strategies. Machine learning techniques have been explored in recent years with a specific focus on the assessment and prediction of multiple suicide-related outcomes, showing promising advancements. This study aims to assess and summarize current research and provides a comprehensive review regarding the application of machine learning techniques in assessing and predicting suicidal ideation, attempts, and mortality among members of military and veteran populations.
Methods
A keyword search using PubMed, IEEE, ACM, and Google Scholar was conducted, and the PRISMA protocol was adopted for relevant study selection. Peer-reviewed original research in English targeting the assessment or prediction of suicide-related outcomes among service members and veteran populations was included. 1,110 studies were retrieved, and 32 satisfied the inclusion criteria and were included.
Results
Thirty-two articles met the inclusion criteria. Despite these studies exhibiting significant variability in sample characteristics, data modalities, specific suicide-related outcomes, and the machine learning technologies employed, they consistently identified risk factors relevant to mental health issues such as depression, post-traumatic stress disorder (PTSD), suicidal ideation, prior attempts, physical health problems, and demographic characteristics. Machine learning models applied in this area have demonstrated reasonable predictive accuracy and have verified, on a large scale, risk factors previously detected by more manual analytic methods. Additional research gaps still exist. First, many studies have overlooked metrics that distinguish between false positives and negatives, such as positive predictive value and negative predictive value, which are crucial in the context of suicide prevention policies. Second, more dedicated approaches to handling survival and longitudinal data should be explored. Lastly, most studies focused on machine learning methods, with limited discussion of their connection to clinical rationales.
Conclusion
In sum, machine learning analyses have identified risk factors associated with suicide in military populations, which span a wide range of psychological, biological, and sociocultural factors, highlighting the complexities involved in assessing suicide risk among service members and veterans. Some differences were noted between males and females. The diversity of these factors also demonstrates that effective prevention strategies must be comprehensive and flexible.
期刊介绍:
The Journal of Biomedical Informatics reflects a commitment to high-quality original research papers, reviews, and commentaries in the area of biomedical informatics methodology. Although we publish articles motivated by applications in the biomedical sciences (for example, clinical medicine, health care, population health, and translational bioinformatics), the journal emphasizes reports of new methodologies and techniques that have general applicability and that form the basis for the evolving science of biomedical informatics. Articles on medical devices; evaluations of implemented systems (including clinical trials of information technologies); or papers that provide insight into a biological process, a specific disease, or treatment options would generally be more suitable for publication in other venues. Papers on applications of signal processing and image analysis are often more suitable for biomedical engineering journals or other informatics journals, although we do publish papers that emphasize the information management and knowledge representation/modeling issues that arise in the storage and use of biological signals and images. System descriptions are welcome if they illustrate and substantiate the underlying methodology that is the principal focus of the report and an effort is made to address the generalizability and/or range of application of that methodology. Note also that, given the international nature of JBI, papers that deal with specific languages other than English, or with country-specific health systems or approaches, are acceptable for JBI only if they offer generalizable lessons that are relevant to the broad JBI readership, regardless of their country, language, culture, or health system.