Triple Transcranial Static Magnetic Field Stimulation System ("SHIN jiba") Modulates the Neural Activity of the Lumbar Spinal Cord: A Cross-over and Single-Blind Study in Healthy Subjects.

IF 3.2 3区医学 Q2 CLINICAL NEUROLOGY

Neuromodulation Pub Date : 2025-05-15 DOI:10.1016/j.neurom.2025.04.006

Haruki Hoshi, Sumiya Shibata, Tatsuya Mima, Hideaki Onishi

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引用次数: 0

Abstract

Objectives: The triple transcranial static magnetic field stimulation (tSMS) system (SHIN jiba), a new form of tSMS, can generate a stronger magnetic field that reaches deeper regions than the conventional tSMS method. Although SHIN jiba suppresses the neural activity of the brain, the neuromodulatory effects on the spinal cord remain unclear. The aim of this study was to investigate the effects of SHIN jiba on the activity of spinal cord circuits and the ascending neural pathways in the lumbar spinal cord by measuring H-reflex and somatosensory evoked potentials (SEPs).

Materials and methods: This study comprised two experiments involving 19 healthy subjects and an additional experiment involving 15 healthy subjects. All experiments were cross-over and single-blind studies. In all experiments, SHIN jiba or sham stimulation was applied over the lumbar region (between the 11th and 12th thoracic vertebrae) for 20 minutes. In experiment 1, H-reflex after the electrical stimulation of the right tibial nerve was recorded before, immediately after, and 15 minutes after the intervention. In experiment 2, SEPs after the electrical stimulation of the right posterior tibial nerve were recorded at the same point as experiment 1.

Results: The H-reflex amplitude was significantly suppressed immediately after SHIN jiba stimulation for 20 minutes. In contrast, the SEP amplitudes did not change before and after SHIN jiba stimulation.

Conclusions: These findings suggest that SHIN jiba has different effects on the activity of spinal cord circuits and the ascending neural pathways in the lumbar spinal cord. SHIN jiba can be a new tool for modulating the neural activity of the spinal cord.

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三重经颅静电磁场刺激系统（“SHIN jiba”）调节腰椎脊髓的神经活动：一项健康受试者的交叉和单盲研究。

目的：三重经颅静态磁场刺激系统（SHIN jiba）是一种新型的经颅静态磁场刺激方法，它比传统的经颅静态磁场刺激方法产生更强的磁场，到达更深的区域。虽然胫刺能抑制大脑的神经活动，但其对脊髓的神经调节作用尚不清楚。本研究的目的是通过测量h反射和体感诱发电位（SEPs）来研究健脾刺巴对脊髓回路活动和腰椎上行神经通路的影响。材料和方法：本研究包括两个实验，19名健康受试者和一个附加实验，15名健康受试者。所有实验均为交叉和单盲研究。在所有实验中，在腰椎区域（第11和第12胸椎之间）施加胫束或假刺激20分钟。实验1记录干预前、干预后、干预后15分钟电刺激右胫神经后的h反射。实验2记录右侧胫后神经电刺激后与实验1同一点的sep。结果：胫筋刺激20分钟后，h反射振幅立即被明显抑制。而刺激前后SEP振幅无明显变化。结论：这些结果表明，胫束对脊髓回路和腰椎上行神经通路的活动有不同的影响。胫刺可以成为调节脊髓神经活动的新工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuromodulation 医学-临床神经学

CiteScore

6.40

自引率

3.60%

发文量

978

审稿时长

54 days

期刊介绍： Neuromodulation: Technology at the Neural Interface is the preeminent journal in the area of neuromodulation, providing our readership with the state of the art clinical, translational, and basic science research in the field. For clinicians, engineers, scientists and members of the biotechnology industry alike, Neuromodulation provides timely and rigorously peer-reviewed articles on the technology, science, and clinical application of devices that interface with the nervous system to treat disease and improve function.