Pelvic mass with isolated supratentorial brain parenchymal metastasis - An unusual presentation of Neuroblastoma: A case report

Abstract

Background

Central nervous system (CNS) metastasis in neuroblastoma (NBL) is rare, typically occurring at the time of disease progression or relapse. Isolated CNS metastasis at diagnosis is even rarer and can present a diagnostic challenge. It is generally associated with a poor prognosis, necessitating aggressive treatment.

Case report

We report a case of neuroblastoma with an unusual presentation, featuring a pelvic primary tumor and a solitary brain parenchymal metastasis—both uncommon sites for NBL.

Conclusion

Although CNS metastasis is rare, a high index of suspicion with appropriate diagnostic workup is crucial for early diagnosis. The prognosis in these cases is generally poor, requiring a multidisciplinary treatment approach, including chemotherapy, surgery, and radiotherapy, to improve survival outcomes.