Cow's Milk Allergy and Associated Factors Among Children in Abha City, Saudi Arabia - A Retrospective Case Control Study.

IF 3.7 3区 医学 Q2 ALLERGY
Journal of Asthma and Allergy Pub Date : 2025-05-07 eCollection Date: 2025-01-01 DOI:10.2147/JAA.S519523
Nawaf Khalid Alqurashi, Syed Esam Mahmood, Abdullah Alsabaani, Ausaf Ahmad, Mohammad Suhail Khan, Ayed A Shati
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引用次数: 0

Abstract

Introduction: Cow's Milk Allergy (CMA) is the most common food allergy among children. The global prevalence of CMA ranges from 1.8% to 7.5% among children. Data regarding CMA is scarce and only a few studies have been conducted in Saudi Arabia. Therefore, this study was undertaken to determine the factors associated with CMA among children in Abha city and to explore the knowledge and practice regarding CMA among parents in Abha city.

Methods: This retrospective one-year case control study was conducted amongst children with CMA (cases) and healthy children without CMA (controls) and their parents attending Abha Maternity and Children Hospital, Saudi Arabia. Data regarding CMA was extracted from the hospital medical records. A validated questionnaire was used to collect detailed information from the identified cases and controls after obtaining informed consent. SPSS software was used for data analysis.

Results: The study groups consisted of 31 cases and 37 controls. Children between 0 and 36 months of age were included. The male-to-female ratio was 1:1. The parent's knowledge level was good regarding the association between early introduction of cow's milk and increased risk of CMA (Mean Score: 3.96). Having a sibling with a CMA is actually a risk factor for developing CMA (P-value = 0.03).

Conclusion: To reduce the risk of CMA, the study recommends dietary strategies that exclude CMA allergens and the use of suitable alternative milk formulas. It highlights the protective role of breastfeeding and advises against the early introduction of cow's milk formulas during infancy. Furthermore, the study advocates for hospital nurseries and new parents to refrain from administering artificial milk formulas to newborns.

沙特阿拉伯阿卜哈市儿童牛奶过敏及相关因素:回顾性病例对照研究
牛奶过敏(CMA)是儿童中最常见的食物过敏。全球儿童CMA患病率为1.8%至7.5%。关于CMA的数据很少,仅在沙特阿拉伯进行了少量研究。因此,本研究旨在确定阿卜哈市儿童CMA的相关因素,并探讨阿卜哈市家长关于CMA的知识和实践。方法:对沙特阿拉伯Abha妇幼医院的CMA患儿(病例)和未患CMA的健康患儿(对照组)及其父母进行为期一年的回顾性病例对照研究。关于CMA的数据是从医院病历中提取的。在获得知情同意后,使用一份有效的问卷收集已确定病例和对照的详细信息。采用SPSS软件进行数据分析。结果:研究组31例,对照组37例。年龄在0到36个月之间的儿童被包括在内。男女比例为1:1。家长对早期引入牛奶与CMA风险增加关系的认知水平较好(平均得分:3.96)。兄弟姐妹患有CMA实际上是患CMA的危险因素(p值= 0.03)。结论:为了降低CMA的风险,研究建议排除CMA过敏原的饮食策略,并使用合适的替代奶粉配方。它强调了母乳喂养的保护作用,并建议不要在婴儿期过早引入牛奶配方。此外,该研究提倡医院托儿所和新父母避免给新生儿使用人工配方奶粉。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Asthma and Allergy
Journal of Asthma and Allergy Medicine-Immunology and Allergy
CiteScore
5.30
自引率
6.20%
发文量
185
审稿时长
16 weeks
期刊介绍: An international, peer-reviewed journal publishing original research, reports, editorials and commentaries on the following topics: Asthma; Pulmonary physiology; Asthma related clinical health; Clinical immunology and the immunological basis of disease; Pharmacological interventions and new therapies. Although the main focus of the journal will be to publish research and clinical results in humans, preclinical, animal and in vitro studies will be published where they shed light on disease processes and potential new therapies.
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