Osteomyelitis of the talus in infants following Bacillus Calmette-Guérin (BCG) vaccination.

Abstract

Osteomyelitis caused by Bacillus Calmette-Guerin (BCG) is a rare complication of Mycobacterium bovis vaccination. Lesions are usually localized in the metaphysis or epiphysis of long bones, but rarely affect the foot. This report describes two cases of BCG osteomyelitis involving the talus in infants of 13 months and eight months old. BCG-osteomyelitis should be suspected in children under two years of age with insidious osteomyelitis, accompanied with characteristic imaging findings.