Gabriela Corati Touguinha, Alberto E Gonzales-Ccoscco, Leonardo Pessoa da Silva, Henrique Trombini, Heitor Ribeiro Birnfeld, Luzia Fernandes Millão, Romulo Rocha Santos, José Fernando Marquez Pachas, Oliver Paucar, Carmen Calcina, Mirko Salomón Alva-Sánchez
{"title":"Comparative evaluation of intraoral stent materials: dosimetric response analysis.","authors":"Gabriela Corati Touguinha, Alberto E Gonzales-Ccoscco, Leonardo Pessoa da Silva, Henrique Trombini, Heitor Ribeiro Birnfeld, Luzia Fernandes Millão, Romulo Rocha Santos, José Fernando Marquez Pachas, Oliver Paucar, Carmen Calcina, Mirko Salomón Alva-Sánchez","doi":"10.1088/2057-1976/add6ac","DOIUrl":null,"url":null,"abstract":"<p><p><i>Purpose</i>. To evaluate and compare the dosimetric properties of various materials used in intraoral stents, with a particular focus on their interaction with a 6 MV photon beam in head and neck cancer radiotherapy.<i>Materials and Methods</i>. Experimental irradiation and computational simulation methods were employed to analyze the interaction of various materials with a 6 MV photon beam used in an intraoral procedure. A head phantom, cylindrical in shape and divided into 1 cm plates, was used along with circular PMMA plates and polystyrene to simulate an intraoral procedure. Radiochromic film (EBT3) was used to evaluate the dose-response of PMMA and PET-G materials with thicknesses of 1, 2, and 3 mm, irradiated under a 10 × 10 cm<sup>2</sup>field size at a 100 cm source-to-skin distance (SSD). The PENELOPE code was used to simulate the dosimetric properties of PMMA, PET-G, EVA, PDMS, and PVDF based on their chemical compositions.<i>Results</i>. A maximum divergence of 4.2% was observed between PET-G and PMMA at a thickness of 3 mm during the experimental procedure. Additionally, a maximum difference of 1.2% was noted when comparing the simulated percentage depth dose curves. Discrepancies of up to 10% were found between experimental irradiation and simulations in polystyrene regions, likely due to the sensitivity of the film to incident fluence. When comparing the simulated materials (PMMA, PET-G, EVA, PDMS, and PVDF), the largest divergence observed was 20% at the surface of the phantom and did not exceed 15% at depths under 10 cm, specifically between PVDF and PMMA. For all other materials, the divergence remained below 10% across all regions.<i>Conclusions</i>. The results suggest that all the materials evaluated for intraoral stent fabrication can be effectively analyzed using the simulation code. PET-G, EVA, and PDMS showed dose-response variations of less than 10%, which should be considered when calculating doses in the treatment system planning, as stents made from these materials may increase the dose to nearby organs.</p>","PeriodicalId":8896,"journal":{"name":"Biomedical Physics & Engineering Express","volume":" ","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical Physics & Engineering Express","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1088/2057-1976/add6ac","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose. To evaluate and compare the dosimetric properties of various materials used in intraoral stents, with a particular focus on their interaction with a 6 MV photon beam in head and neck cancer radiotherapy.Materials and Methods. Experimental irradiation and computational simulation methods were employed to analyze the interaction of various materials with a 6 MV photon beam used in an intraoral procedure. A head phantom, cylindrical in shape and divided into 1 cm plates, was used along with circular PMMA plates and polystyrene to simulate an intraoral procedure. Radiochromic film (EBT3) was used to evaluate the dose-response of PMMA and PET-G materials with thicknesses of 1, 2, and 3 mm, irradiated under a 10 × 10 cm2field size at a 100 cm source-to-skin distance (SSD). The PENELOPE code was used to simulate the dosimetric properties of PMMA, PET-G, EVA, PDMS, and PVDF based on their chemical compositions.Results. A maximum divergence of 4.2% was observed between PET-G and PMMA at a thickness of 3 mm during the experimental procedure. Additionally, a maximum difference of 1.2% was noted when comparing the simulated percentage depth dose curves. Discrepancies of up to 10% were found between experimental irradiation and simulations in polystyrene regions, likely due to the sensitivity of the film to incident fluence. When comparing the simulated materials (PMMA, PET-G, EVA, PDMS, and PVDF), the largest divergence observed was 20% at the surface of the phantom and did not exceed 15% at depths under 10 cm, specifically between PVDF and PMMA. For all other materials, the divergence remained below 10% across all regions.Conclusions. The results suggest that all the materials evaluated for intraoral stent fabrication can be effectively analyzed using the simulation code. PET-G, EVA, and PDMS showed dose-response variations of less than 10%, which should be considered when calculating doses in the treatment system planning, as stents made from these materials may increase the dose to nearby organs.
期刊介绍:
BPEX is an inclusive, international, multidisciplinary journal devoted to publishing new research on any application of physics and/or engineering in medicine and/or biology. Characterized by a broad geographical coverage and a fast-track peer-review process, relevant topics include all aspects of biophysics, medical physics and biomedical engineering. Papers that are almost entirely clinical or biological in their focus are not suitable. The journal has an emphasis on publishing interdisciplinary work and bringing research fields together, encompassing experimental, theoretical and computational work.