From Ramsay Hunt to Parotid Cancer: A Case Report.

Meredith H Cummings, Kai-Lin You, Marci L Nilsen
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Abstract

Diagnosis of head and neck malignancies remains challenging given the complexity and heterogeneity of the organs and involved anatomical features. Additionally, the presenting symptoms of head and neck cancer may often be vague, mimicking symptoms of less serious illnesses. The following case highlights these challenges. The patient presented to his primary care physician with right facial paralysis involving difficulty closing his eye, as well as intermittent right ear pain. The patient was referred to neurology for a workup to diagnose Lyme Disease or Ramsay Hunt Auricularis. The patient was initially diagnosed with and treated for Ramsay Hunt Auricularis. Despite the treatment, the patient suffered two falls from a loss of consciousness. The cardiologist consulted in the emergency department noted no cardiac etiology. Ultimately, a Computerized Tomography scan and additional imaging revealed a parotid lesion, and the patient was diagnosed with salivary gland carcinoma. The tumor was encircling the internal carotid artery and was subsequently deemed inoperable. No distant metastases were noted. The patient was treated with concurrent chemoradiation using carboplatin and paclitaxel, and leuprolide for androgen receptor-positive cancer. The patient completed this treatment and continues leuprolide every three months. His most recent Positron Emission Tomography scan revealed no evidence of residual disease or recurrent/metastatic disease. The patient still experiences significant long-term treatment effects, such as lymphedema, trismus, and peripheral neuropathy, for which he undergoes rehabilitation services. This unique case is a prime example of the complicated diagnosis and treatment trajectories for patients with head and neck cancer. Frequent follow-up and long-term multidisciplinary care are essential to manage symptoms associated with treatment for all individuals with head and neck cancers.

从拉姆齐·亨特到腮腺癌:一个病例报告。
头颈部恶性肿瘤的诊断仍然具有挑战性的复杂性和异质性的器官和涉及的解剖特征。此外,头颈癌的症状通常很模糊,类似于不太严重的疾病的症状。下面的案例突出了这些挑战。患者向初级保健医生提出右侧面瘫,包括闭眼困难,以及间歇性右耳疼痛。患者被转介到神经内科进行检查,以诊断莱姆病或拉姆齐·亨特耳病。患者最初被诊断为拉姆齐·亨特耳病并接受治疗。尽管接受了治疗,病人还是因失去知觉而跌倒了两次。在急诊科咨询的心脏病专家没有注意到心脏病因。最终,计算机断层扫描和附加成像显示腮腺病变,患者被诊断为唾液腺癌。肿瘤环绕颈内动脉,随后被认为不能手术。未见远处转移。患者同时接受卡铂和紫杉醇的放化疗,以及雄激素受体阳性癌症的leuprolide治疗。患者完成了这项治疗,并每三个月继续使用leuprolide。他最近的正电子发射断层扫描显示没有残留疾病或复发/转移性疾病的证据。患者仍然经历显著的长期治疗效果,如淋巴水肿、牙关和周围神经病变,为此他接受康复服务。这个独特的病例是头颈癌患者复杂的诊断和治疗轨迹的一个主要例子。频繁的随访和长期的多学科护理对于所有头颈癌患者治疗相关症状的管理至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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