Transcranial Alternating Current Stimulation and Cognitive Training Enhanced Performance and Theta Activity in Adults With Cognitive Impairment.

IF 3.2 2区心理学 Q1 PSYCHOLOGY, MULTIDISCIPLINARY

Psicothema Pub Date : 2025-05-01 DOI:10.70478/psicothema.2025.37.11

Susana Cid-Fernández, Ana Nieto-Vieites, Arturo X Pereiro, Fernando Díaz

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Abstract

Background: Age-related cognitive decline is rising due to longer life expectancy, necessitating new treatments as current drugs are ineffective and costly. Transcranial alternating current stimulation at the theta frequency (theta-tACS) has shown promise in enhancing cognitive function in both young and elderly adults, but its effectiveness in those with cognitive decline is not well-studied.

Method: This study involved 27 participants with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and dementia, who underwent multiple sessions combining computerized cognitive training with theta-tACS to assess its efficacy. Participants were randomly assigned to either a real-tACS or sham-tACS group. Before and after treatment, they completed several cognitive tasks, and their behavioral and EEG data were collected.

Results: Only the real-tACS group improved in the oddball task and exhibited increased event-related EEG amplitude in the theta range.

Conclusions: These findings suggest that theta-tACS can improve cognitive performance in individuals with cognitive decline at both behavioral and psychophysiological levels, supporting its potential for alleviating cognitive decline in elderly populations.

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经颅交流电刺激和认知训练可提高认知障碍成人的表现和θ波活动。

背景：由于预期寿命延长，与年龄相关的认知能力下降正在上升，由于目前的药物无效且昂贵，因此需要新的治疗方法。经颅交流电刺激在theta频率（theta- tacs）显示出增强年轻人和老年人认知功能的希望，但其对认知衰退患者的有效性尚未得到充分研究。方法：本研究纳入了27名主观认知能力下降（SCD）、轻度认知障碍（MCI）和痴呆的参与者，他们接受了多次将计算机认知训练与theta-tACS相结合的训练，以评估其疗效。参与者被随机分配到真实或虚假的tacs组。在治疗前后，他们分别完成多项认知任务，并收集他们的行为和脑电图数据。结果：只有real-tACS组在奇球任务中有所改善，theta范围内的事件相关EEG振幅有所增加。结论：这些研究结果表明，theta-tACS可以在行为和心理生理水平上改善认知衰退个体的认知表现，支持其缓解老年人认知衰退的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Psicothema PSYCHOLOGY, MULTIDISCIPLINARY-

CiteScore

6.50

自引率

16.70%

发文量

审稿时长

24 weeks

期刊介绍： La revista Psicothema fue fundada en Asturias en 1989 y está editada conjuntamente por la Facultad y el Departamento de Psicología de la Universidad de Oviedo y el Colegio Oficial de Psicólogos del Principado de Asturias. Publica cuatro números al año. Se admiten trabajos tanto de investigación básica como aplicada, pertenecientes a cualquier ámbito de la Psicología, que previamente a su publicación son evaluados anónimamente por revisores externos. Psicothema está incluida en las bases de datos nacionales e internacionales más relevantes, entre las que cabe destacar Psychological Abstracts, Current Contents y MEDLINE/Index Medicus, entre otras. Además, figura en las listas de Factor de Impacto del Journal Citation Reports. Psicothema es una revista abierta a cualquier enfoque u orientación psicológica que venga avalada por la fuerza de los datos y los argumentos, y en la que encuentran acomodo todos los autores que sean capaces de convencer a los revisores de que sus manuscritos tienen la calidad para ser publicados. Psicothema es una revista de acceso abierto lo que significa que todo el contenido está a disposición de cualquier usuario o institución sin cargo alguno. Los usuarios pueden leer, descargar, copiar, distribuir, imprimir, buscar, o realizar enlaces a los textos completos de esta revista sin pedir permiso previo al editor o al autor, siempre y cuando la fuente original sea referenciada. Para acervos y repositorios, se prefiere que la cobertura se realice mediante enlaces a la propia web de Psicothema. Nos parece que una apuesta decidida por la calidad es el mejor modo de servir a nuestros lectores, cuyas sugerencias siempre serán bienvenidas.