Rodin: a streamlined metabolomics data analysis and visualization tool.

Abstract

Summary: Recent advances in high-resolution mass spectrometry have revolutionized metabolomics, enabling the profiling of hundreds of thousands of metabolic features in a single experiment, with widespread applications across health sciences. To streamline analysis of metabolomics data, we developed Rodin, a Python-based application offering fast, efficient processing of large datasets via a web interface or programming library. Rodin integrates multiple stages of analysis, including feature preprocessing, statistical testing, interactive visualizations, and pathway analysis, generating outputs while tracking user-defined parameters within a single page. By enhancing the accessibility of tools for metabolomics data analysis, Rodin not only streamlines the workflow but also enhances analytic throughput by enabling a broader range of users to perform these analyses. Compared to other tools, Rodin excels in user-friendliness, ease of access, and seamless integration of multiple functionalities, enabling reproducible, efficient workflows for users of all computational skill levels.

Availability and implementation: Web interface-https://rodin-meta.com/. Python library-https://github.com/BM-Boris/rodin.