Surgery for breast cancer liver and lung metastases: A review.

IF 2.5 3区 医学 Q1 SURGERY
Ellen Hansson, Charlotta Wadsten, Oskar Hemmingsson
{"title":"Surgery for breast cancer liver and lung metastases: A review.","authors":"Ellen Hansson, Charlotta Wadsten, Oskar Hemmingsson","doi":"10.1177/14574969251333526","DOIUrl":null,"url":null,"abstract":"<p><strong>Background and objective: </strong>Breast cancer liver and lung metastases are common and associated with poor prognosis. Personalized medical treatment of advanced breast cancer, based on established predictive factors, has improved survival during the last decades. In contrast, there is no consensus regarding indications for surgery. The aim of this narrative review is to summarize the current knowledge on the outcome of surgical treatments for breast cancer liver and lung metastases.</p><p><strong>Method: </strong>A narrative review of existing evidence for diagnosis and treatment of breast cancer liver and lung metastases.</p><p><strong>Results: </strong>There are no randomized trials to evaluate surgery as an adjunct to medical treatment. In this review, data are reported from case-control studies and meta-analyses on surgery for liver and lung metastases. Selected patients have an improved survival after surgery compared to those who only received medical treatment. The survival benefit is, however, uncertain when adjusting for prognostic factors, and prospective trials are warranted. Anecdotal cases have long-term survival and surgery is safe.</p><p><strong>Conclusion: </strong>Surgery for breast cancer liver and lung metastases may be considered in selected cases within prospective studies.</p>","PeriodicalId":49566,"journal":{"name":"Scandinavian Journal of Surgery","volume":" ","pages":"14574969251333526"},"PeriodicalIF":2.5000,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scandinavian Journal of Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/14574969251333526","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"SURGERY","Score":null,"Total":0}
引用次数: 0

Abstract

Background and objective: Breast cancer liver and lung metastases are common and associated with poor prognosis. Personalized medical treatment of advanced breast cancer, based on established predictive factors, has improved survival during the last decades. In contrast, there is no consensus regarding indications for surgery. The aim of this narrative review is to summarize the current knowledge on the outcome of surgical treatments for breast cancer liver and lung metastases.

Method: A narrative review of existing evidence for diagnosis and treatment of breast cancer liver and lung metastases.

Results: There are no randomized trials to evaluate surgery as an adjunct to medical treatment. In this review, data are reported from case-control studies and meta-analyses on surgery for liver and lung metastases. Selected patients have an improved survival after surgery compared to those who only received medical treatment. The survival benefit is, however, uncertain when adjusting for prognostic factors, and prospective trials are warranted. Anecdotal cases have long-term survival and surgery is safe.

Conclusion: Surgery for breast cancer liver and lung metastases may be considered in selected cases within prospective studies.

乳腺癌肝、肺转移的手术治疗综述。
背景与目的:乳腺癌肝、肺转移较为常见,且预后较差。在过去几十年中,基于已确定的预测因素对晚期乳腺癌进行个性化医疗治疗,提高了生存率。相比之下,对于手术指征没有共识。这篇叙述性综述的目的是总结目前关于乳腺癌肝和肺转移的手术治疗结果的知识。方法:对现有乳腺癌肝、肺转移的诊断和治疗证据进行综述。结果:没有随机试验来评价手术作为药物治疗的辅助手段。在这篇综述中,数据来自病例对照研究和肝和肺转移手术的荟萃分析。与那些只接受药物治疗的患者相比,被选中的患者在手术后生存率更高。然而,当调整预后因素时,生存获益是不确定的,前瞻性试验是有必要的。轶事病例有长期生存和手术是安全的。结论:在前瞻性研究中,选择性病例可以考虑对乳腺癌肝和肺转移进行手术治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
5.50
自引率
4.20%
发文量
37
审稿时长
6-12 weeks
期刊介绍: The Scandinavian Journal of Surgery (SJS) is the official peer reviewed journal of the Finnish Surgical Society and the Scandinavian Surgical Society. It publishes original and review articles from all surgical fields and specialties to reflect the interests of our diverse and international readership that consists of surgeons from all specialties and continents.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信