An Analysis of Exposure Keratopathy Cases to Promote Changes in Eye Care Practice in Intensive Care Units.

Susanna Betti, Harrison Bell, Jonathan Glatt, Erika J Yoo, David A Oxman
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Abstract

Exposure keratopathy (EK) is corneal damage from prolonged environmental exposure. If untreated, EK can lead to corneal scarring and/or blindness. Critically ill patients are at high risk. A case of EK in our intensive care unit led us to investigate the incidence of EK in our critical care units and understand the interventions needed to reduce its impact. We found 44 cases of EK over 3 years. 95% received mechanical ventilation and 32% received paralytic agents. Average time to diagnosis was 15.8 days from intensive care unit admission. More than a quarter (27%) of patients had severe EK at diagnosis, and 52% of patients had received prior eye care. EK occurred frequently in our critical care units. Many subjects did not receive prophylaxis and disease was diagnosed at a late stage. To address this, we plan a 3-pronged approach focusing on prevention, early recognition, and timely initiation of treatment.

暴露性角膜病变病例分析促进重症监护病房眼科护理实践的改变。
暴露性角膜病变(EK)是长期暴露在环境中的角膜损伤。如果不治疗,EK可导致角膜瘢痕和/或失明。危重病人的风险很高。我们重症监护室的一个EK病例使我们调查了EK在重症监护室的发病率,并了解了减少其影响所需的干预措施。我们发现44例EK超过3年。95%接受机械通气,32%接受麻痹剂治疗。从重症监护病房入院到诊断的平均时间为15.8天。超过四分之一(27%)的患者在诊断时患有严重的EK, 52%的患者先前接受过眼科护理。EK经常发生在我们的重症监护病房。许多受试者没有接受预防治疗,疾病在晚期才被诊断出来。为了解决这个问题,我们计划采取三管齐下的方法,重点是预防、早期识别和及时开始治疗。
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