Risk of Relapse Following Discharge from Non-Hospital Residential Opioid Use Disorder Treatment: A Systematic Review of Studies Published from 2018 to 2022.

IF 5.1 Q1 SUBSTANCE ABUSE
Substance Abuse and Rehabilitation Pub Date : 2025-04-23 eCollection Date: 2025-01-01 DOI:10.2147/SAR.S440214
Orrin D Ware, Gabriella Rose Geiger, Veronica D Rivas, Miracle A Macias Burgos, Lea Nehme-Kotocavage, Tara G Bautista
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引用次数: 0

Abstract

Relapsing on opioids after residential treatment may involve fatal outcomes, considering the potential for reduced tolerance and the potency of fentanyl in the illicit opioid market. The present paper examines recent literature on the risk of relapse among adults with opioid use disorder after discharge from residential treatment. We searched for published studies from 2018 to 2022 through database searches, including CINAHL, PsychINFO, PubMed, and Scopus. Across the N=10 studies included in this review, returning to substance use after residential treatment was captured differently, including self-report, hair samples, and urine samples. Follow-up relapse data after discharging from treatment was also captured across different time periods of included studies ranging from one month to six months. Variability was also identified in the percentage of individuals who relapsed after treatment, ranging from 0% to 95%. Considering the potential for a fatal overdose in the current fentanyl era, it is imperative to provide resources during residential treatment that can reduce the risk of relapse after discharge.

非医院住院阿片类药物使用障碍治疗出院后复发的风险:2018年至2022年发表的研究的系统综述
考虑到芬太尼在非法阿片类药物市场上的耐受性和效力降低的可能性,住院治疗后再次使用阿片类药物可能涉及致命的后果。本文研究了最近关于阿片类药物使用障碍成人住院治疗出院后复发风险的文献。我们通过数据库检索检索了2018年至2022年发表的研究,包括CINAHL、PsychINFO、PubMed和Scopus。在本综述中纳入的N=10项研究中,住院治疗后重新使用药物的情况不同,包括自我报告、头发样本和尿液样本。从治疗出院后的随访复发数据也在不同的时间段被捕获,从一个月到六个月不等。治疗后复发的个体百分比也存在差异,从0%到95%不等。考虑到当前芬太尼时代致命过量的可能性,必须在住院治疗期间提供资源,以减少出院后复发的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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