[Research progress of long noncoding RNA in atopic dermatitis].

Q4 Medicine

中华医学遗传学杂志 Pub Date : 2025-02-10 DOI:10.3760/cma.j.cn511374-20241024-00554

Xin Liu, Xinying Cai

引用次数: 0

Abstract

Long noncoding RNA (lncRNA) is a type of RNA that is longer than 200 nucleotides and does not encode proteins. Atopic dermatitis (AD) is a common chronic inflammatory skin disease. Genetic susceptibility, damaged skin barrier and immune imbalance play important roles in its pathogenesis. Studies have shown that abnormal expression of lncRNA plays an important role in the development of many human diseases. In recent years, it has been found that various lncRNAs are abnormally expressed in AD patients and are involved in the development of AD. This paper reviews the research progress of lncRNAs in AD, aiming to provide more reference for the pathogenesis and treatment of AD.

查看原文本刊更多论文

[长链非编码RNA在特应性皮炎中的研究进展]。

长链非编码RNA （lncRNA）是一种长度超过200个核苷酸且不编码蛋白质的RNA。特应性皮炎（AD）是一种常见的慢性炎症性皮肤病。遗传易感性、皮肤屏障受损和免疫失衡在其发病机制中起重要作用。研究表明，lncRNA的异常表达在人类许多疾病的发生发展中起着重要作用。近年来，人们发现多种lncrna在AD患者中异常表达，参与了AD的发展。本文综述了lncrna在AD中的研究进展，旨在为AD的发病机制和治疗提供更多参考。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

中华医学遗传学杂志 Medicine-Medicine (all)

CiteScore

0.50

自引率

0.00%

发文量

9521

期刊介绍： Chinese Journal of Medical Genetics is a medical journal, founded in 1984, under the supervision of the China Association for Science and Technology, sponsored by the Chinese Medical Association (hosted by Sichuan University), and is now a monthly magazine, which attaches importance to academic orientation, adheres to the scientific, scholarly, advanced, and innovative, and has a certain degree of influence in the industry. Chinese Journal of Medical Genetics is a journal of Peking University, and is now included in Peking University Journal (Chinese Journal of Humanities and Social Sciences), CSCD Source Journals of Chinese Science Citation Database (with extended version), Statistical Source Journals (China Science and Technology Dissertation Outstanding Journals), Zhi.com (in Chinese), Wipu (in Chinese), Wanfang (in Chinese), CA Chemical Abstracts (U.S.), JST (Japan Science and Technology Science and Technology), and JST (Japan Science and Technology Science and Technology Research Center). ), JST (Japan Science and Technology Agency), Pж (AJ) Abstracts Journal (Russia), Copernicus Index (Poland), Cambridge Scientific Abstracts, Abstracts and Citation Database, Abstracts Magazine, Medical Abstracts, and so on.