The burden of hand trauma surgery on primary care in the United Kingdom: a nation-wide analysis of antibiotic and opioid prescriptions.

Justin Cr Wormald, Jennifer Ce Lane, Marti Català, Antonella Delmestri, Jonathan Cook, Jeremy N Rodrigues, Matthew L Costa, Daniel Prieto-Alhambra
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Abstract

Although surgical site infection (SSI) risk after hand trauma surgery is around 5%, the severity of these infections is not known. The risk of superficial SSI in a cohort study was evaluated using NHS UK-wide primary care records (n = 641,223), using the Clinical Practice Research Datalink GOLD database. Within this cohort, a subcohort of those who had undergone a hand surgery operation for trauma were identified (n = 3,088). Antibiotic and analgesic prescriptions were analysed at 30 and 90 days postoperatively. By 30 days, 6.2% had been prescribed antibiotics appropriate for SSI, rising to 14.4% (CI [13.2 to 15.8]) by 90 days. By 30 days, 10% had been prescribed opioid analgaesia and by 90 days this had increased to 13.8%. Antibiotics prescriptions for SSI in primary care are substantially higher than the NICE estimate for SSI overall and the expected risk in hand trauma. The implications of this study are that many patients are receiving treatment for SSI in primary care and may be in more pain, for longer, than we expect. Further exploration of this is warranted and future research in hand trauma surgery should capture adverse events occurring outside of the hospital environment.Level of evidence: II.

手部创伤手术对英国初级保健的负担:抗生素和阿片类药物处方的全国范围分析。
虽然手部创伤手术后手术部位感染(SSI)的风险约为5%,但这些感染的严重程度尚不清楚。在一项队列研究中,使用临床实践研究数据链GOLD数据库,使用NHS英国范围内的初级保健记录(n = 641,223)评估浅表SSI的风险。在这个队列中,确定了一个接受过手部创伤手术的亚队列(n = 3088)。术后30和90天分别分析抗生素和镇痛药处方。到30天,有6.2%的人开了适合SSI的抗生素,到90天上升到14.4% (CI[13.2 ~ 15.8])。到30天,10%的人开了阿片类镇痛药,到90天,这一比例上升到13.8%。初级保健中用于SSI的抗生素处方大大高于NICE对SSI总体和手部创伤预期风险的估计。这项研究的意义是,许多患者在初级保健中接受SSI治疗,可能比我们预期的更痛苦,持续时间更长。这方面的进一步探索是有必要的,未来的手部创伤手术研究应该捕捉到在医院环境之外发生的不良事件。证据水平:II。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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