ICRP pregnant-female mesh-type reference computational phantoms part 2: development of maternal phantoms.

IF 3.3 3区 医学 Q2 ENGINEERING, BIOMEDICAL
Bangho Shin, Suhyeon Kim, Chansoo Choi, Hyeonil Kim, Yeon Soo Yeom, Beom Sun Chung, Thang Tat Nguyen, Wesley E Bolch, Sungho Moon, Haegin Han, Chan Hyeong Kim
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Abstract

Objective. In the present study, the pregnant-female mesh-type reference computational phantoms (MRCPs) of the International Commission on Radiological Protection (ICRP) were fully developed in the tetrahedral-mesh format by constructing the maternal phantoms for 8-, 10-, 15-, 20-, 25-, 30-, 35-, and 38 week fetal ages.Approach. The reference blood-inclusive organ dataset (masses, elemental compositions, and densities) and the anthropometric data (rib cage dimensions, spinal curvature and pelvic inclination angle, breast dimensions, and anthropometric parameters) were established, which were then used to develop the maternal phantoms. During the development process, the pregnant-female MRCPs were fully developed by installing the mesh-type fetal phantoms in the maternal uterus considering the shape and position of the fetus.Main results. The dosimetric impact of the phantoms, in terms of fetal dose from maternal radionuclide intake, was investigated by calculating the photon specific absorbed fractions (SAFs) for some selected maternal organs as source regions and the entire fetal phantom as a target region. The results showed that the SAFs for the older fetus were larger than those for the younger fetus when the source-target distance is long, and the opposite trend is observed when the distance is short. These results were observed due to the growth of the fetus.Significance. The pregnant-female MRCPs will serve as the only ICRP reference phantoms representing the pregnant women and fetuses. The comprehensive SAFs dataset will be computed to calculate the ICRP reference dose coefficients for fetal members of the public.

ICRP孕妇-女性网格型参考计算幻影。第2部分:母体幻影的发展。
目标。本研究通过构建胎龄为8、10、15、20、25、30、35和38周的母体模型,以四面体网格格式构建了国际放射防护委员会(ICRP)的孕母参考计算模型(MRCPs)。建立了参考血液包涵器官数据集(质量、元素组成和密度)和人体测量数据(胸腔尺寸、脊柱曲率和骨盆倾角、乳房尺寸和人体测量参数),然后使用这些数据来开发母体幻象。在发育过程中,考虑到胎儿的形态和位置,在母体子宫内安装网状胎模,对孕母MRCPs进行充分发育。主要的结果。通过计算一些选定的母亲器官作为源区和整个胎儿幻影作为靶区的光子特定吸收分数(SAFs),研究了母体放射性核素摄入对胎儿剂量的剂量学影响。结果表明,当源靶距离较长时,大龄胎儿的saf大于幼龄胎儿,而当源靶距离较短时,则相反。这些结果是由于胎儿的生长而观察到的。孕妇-女性MRCPs将作为代表孕妇和胎儿的唯一ICRP参考幻影。将计算综合SAFs数据集,以计算公众胎儿成员的ICRP参考剂量系数。
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来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
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