Comparison of Dexmedetomidine and Midazolam in Sedoanalgesia for Lumbar Facet Radiofrequency Ablation.

IF 2.6 3区医学 Q2 ANESTHESIOLOGY

Clinical Journal of Pain Pub Date : 2025-05-12 DOI:10.1097/AJP.0000000000001298

Mustafa Kurçaloğlu, Pınar Uzun Uslu, Firdevs Yilmazlar, Aygun Jabbarli, Bora Uzuner, Fatih Özkan, Fuat Güldoğuş

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引用次数: 0

Abstract

Objectives: Lumbar facet radiofrequency ablation (LFRA) is a painful procedure. Sedation may be applied to improve patient comfort during the procedure however, deep sedation should be avoided to maintain the patient cooperation. The purpose of this study was to compare dexmedetomidine and midazolam in sedoanalgesia for LFRA.

Methods: Patients planning to undergo LFRA were included in this cross-sectional, observational study. Following a bolus dose, intravenous infusion of dexmedetomidine was administered in Group D, while intravenous midazolam was given in Group M. Intraoperative vital signs, procedural pain severity (Numerical Rating Scale-NRS), Patient Satisfaction Score (PSS), Operator Satisfaction Score (OSS), and complications were recorded.

Results: A total of 96 patients were included in the study. Group D consisted of 47 and Group M of 49 patients. Procedural NRS, PSS, and OSS were significantly in favor of Group D. Mean procedural NRS of Group D was 2.91±2.03, and 4.14±2.17 in Group M ( P =0.005). The rate of unsatisfactory PSS was one (2.1%) in Group D and seven (20%) in Group M ( P =0.03). The rate of unsatisfactory OSS results was two (4.2%) in Group D and sixteen (32.6%) in Group M ( P <0.001). While over-sedation and low oxygen saturation were significantly more frequent in Group M, hypotension was higher in Group D.

Discussion: In sedoanalgesia for LFRA, dexmedetomidine is superior to midazolam with lower procedural pain, higher satisfaction scores and improved patient cooperation. The results of this study can be considered for sedoanalgesia in other interventional pain procedures.

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右美托咪定与咪达唑仑在腰椎关节突射频消融术中镇痛效果的比较。

目的：腰椎关节突射频消融术（LFRA）是一种痛苦的手术。镇静可用于改善患者在手术过程中的舒适度，但应避免深度镇静，以保持患者的配合。本研究的目的是比较右美托咪定和咪达唑仑对LFRA的sedo镇痛效果。方法：计划行LFRA的患者纳入本横断面观察性研究。D组在给药后静脉滴注右美托咪定，m组静脉滴注咪达唑仑，记录术中生命体征、手术疼痛严重程度（数值评定量表- nrs）、患者满意度评分（PSS）、操作者满意度评分（OSS）及并发症。结果：共纳入96例患者。D组47例，M组49例。D组程序性NRS、PSS、OSS均显著优于D组。D组程序性NRS平均为2.91±2.03，M组程序性NRS平均为4.14±2.17 （P =0.005）。PSS不满意率D组为1例（2.1%），M组为7例（20%）（P =0.03）。结果不满意的发生率D组为2例（4.2%），M组为16例（32.6%）。(P)讨论：在LFRA的sedopain中，右美托咪定优于咪达唑仑，手术疼痛更小，满意度评分更高，患者配合度更好。本研究的结果可用于其他介入性疼痛手术中的sedo镇痛。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Journal of Pain 医学-临床神经学

CiteScore

5.40

自引率

3.40%

发文量

118

审稿时长

4-8 weeks

期刊介绍： The Clinical Journal of Pain explores all aspects of pain and its effective treatment, bringing readers the insights of leading anesthesiologists, surgeons, internists, neurologists, orthopedists, psychiatrists and psychologists, clinical pharmacologists, and rehabilitation medicine specialists. This peer-reviewed journal presents timely and thought-provoking articles on clinical dilemmas in pain management; valuable diagnostic procedures; promising new pharmacological, surgical, and other therapeutic modalities; psychosocial dimensions of pain; and ethical issues of concern to all medical professionals. The journal also publishes Special Topic issues on subjects of particular relevance to the practice of pain medicine.