[Humoral immune response against Trichomonas tenax in patients with chronic catarrhal gingivitis before and after specific Fasigyn treatment].

Abstract

The following parameters were studied in 71 subjects, aged from 7 to 38 with chronic catarrhal gingivitis, invaded by T. tenax: oral-hygienic index of Green and Vermillion before the specific Fasigyn treatment and on 3, 7, 14 and 30 days after the treatment; the presence of complement-combining antibodies against T. tenax and the dynamics of antibody synthesis by 3, 6, 12 and 15 month after the treatment. Thirty one subjected with chronic catarrhal gingivitis, non invaded by T tenax were studied as controls. It has been established that in 53.52% of the subjects with chronic catarrhal gingivitis, invaded by T tenax, the inflammatory changes in gingiva disappeared as early as the third day after the specific Fasigyn treatment and in the rest--by 30 day. Higher values of complement-combining antibodies against T. tenax with a titre from 1:40 to 1:2569 were established in 65.34% from the subjects with chronic catarrhal gingivitis, invaded by T. tenax. The titre of antibodies sharpy decreased by month 3 and was normalized by months 6-12 after Fasigyn treatment.