{"title":"Advances in the application of 18F-sodium fluoride PET in the assessment of atherosclerosis.","authors":"Yan Wang, Mingyuan Hou, Taiyang Zuo","doi":"10.1097/MNM.0000000000001988","DOIUrl":null,"url":null,"abstract":"<p><p>Atherosclerosis serves as the primary cause of cardiovascular diseases (CVDs), with its pathological processes encompassing lipid deposition, inflammatory responses, and calcification. Traditional imaging techniques, such as computed tomography angiography and MRI, are primarily utilized for detecting arterial stenosis and calcified plaques, yet they face challenges in accurately assessing plaque activity and instability. 18F-sodium fluoride PET (18F-NaF PET) offers a novel approach for plaque activity and stability assessment by labeling and quantifying arterial wall calcification. This article reviews the advances in the application of 18F-NaF PET in the assessment of atherosclerosis.</p>","PeriodicalId":19708,"journal":{"name":"Nuclear Medicine Communications","volume":" ","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nuclear Medicine Communications","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/MNM.0000000000001988","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Atherosclerosis serves as the primary cause of cardiovascular diseases (CVDs), with its pathological processes encompassing lipid deposition, inflammatory responses, and calcification. Traditional imaging techniques, such as computed tomography angiography and MRI, are primarily utilized for detecting arterial stenosis and calcified plaques, yet they face challenges in accurately assessing plaque activity and instability. 18F-sodium fluoride PET (18F-NaF PET) offers a novel approach for plaque activity and stability assessment by labeling and quantifying arterial wall calcification. This article reviews the advances in the application of 18F-NaF PET in the assessment of atherosclerosis.
期刊介绍:
Nuclear Medicine Communications, the official journal of the British Nuclear Medicine Society, is a rapid communications journal covering nuclear medicine and molecular imaging with radionuclides, and the basic supporting sciences. As well as clinical research and commentary, manuscripts describing research on preclinical and basic sciences (radiochemistry, radiopharmacy, radiobiology, radiopharmacology, medical physics, computing and engineering, and technical and nursing professions involved in delivering nuclear medicine services) are welcomed, as the journal is intended to be of interest internationally to all members of the many medical and non-medical disciplines involved in nuclear medicine. In addition to papers reporting original studies, frankly written editorials and topical reviews are a regular feature of the journal.