Cost utility analysis of acute rehabilitation approaches in the management of traumatic anterior shoulder dislocation.

IF 2.8 Q1 ORTHOPEDICS
Henry Nwankwo, James Mason, Martin Underwood, Helen Parsons, Aminul Haque, David Torgerson, Chetan Modi, Rebecca S Kearney
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引用次数: 0

Abstract

Aims: We aimed to conduct a cost-utility analysis comparing one session of advice, supporting materials, and option to self-refer to physiotherapy with the same advice and materials, plus an additional programme of physiotherapy for people with a first-time, traumatic anterior shoulder dislocation.

Methods: We conducted an economic evaluation within a randomized controlled trial from the UK NHS and personal social services (PSS) perspective. Resources used, and health-related quality of life information, were collected as part of the Acute Rehabilitation following Traumatic anterior shoulder dISlocAtioN (ARTISAN) randomized controlled trial over a 12-month period using patient-completed questionnaires. Incremental costs and quality-adjusted life-years (QALYs) accrued over the follow-up period were calculated and expressed as the incremental cost-effectiveness ratio (ICER). Estimate uncertainty was explored by bootstrapping and graphically displayed on the ICER plane. Net monetary benefits, probability of cost-effectiveness, and expected value of perfect information were explored at a range of willingness-to-pay thresholds and visualized graphically.

Results: Over a 12-month time horizon, incremental costs were £64 (95% CI -61 to 191) and incremental QALYs were 0.019 (95% CI -0.0005 to 0.0375) for the additional programme of physiotherapy. The ICER was £3,373/QALY, suggesting that the programme is cost-effective, although the primary outcome (Oxford Shoulder Instability Score) found little difference six months after a shoulder dislocation. The probability of being cost-effective at a willingness-to-pay threshold of £30,000 per QALY is 95%. Findings need to interpreted with caution given the high rates of missing data at 12 months, due to the final 12-month follow-up being curtailed during the trial. However, the range of sensitivity analyses supports the base case findings.

Conclusion: The within-trial economic evaluation found that the additional physiotherapy programme is likely to be cost-effective. However, given the small and imprecise health gains, the best use of scarce physiotherapy resources needs careful consideration given other current demands on services.

外伤性肩前脱位急性康复治疗的成本效益分析。
目的:我们的目的是进行一项成本-效用分析,比较一个疗程的建议,支持材料,选择自我参考物理治疗与相同的建议和材料,加上一个额外的物理治疗方案,首次创伤性前肩脱位的人。方法:我们从英国国民医疗服务体系和个人社会服务(PSS)的角度进行了一项随机对照试验的经济评估。使用的资源和健康相关的生活质量信息,作为创伤性肩关节前脱位后急性康复(ARTISAN)随机对照试验的一部分,通过患者填写的问卷收集了12个月的时间。计算随访期间累积的增量成本和质量调整生命年(QALYs),并以增量成本-效果比(ICER)表示。估计的不确定度是通过自引导探索和图形显示在ICER平面。净货币收益、成本效益概率和完美信息的期望值在支付意愿阈值范围内进行了探讨,并以图形化的方式进行了可视化。结果:在12个月的时间范围内,额外的物理治疗方案的增量成本为64英镑(95% CI -61至191),增量质量年为0.019英镑(95% CI -0.0005至0.0375)。ICER为3,373英镑/QALY,表明该方案具有成本效益,尽管主要结果(牛津肩部不稳定评分)发现肩关节脱位后6个月差异不大。在每个QALY 30,000英镑的支付意愿阈值下,成本效益的可能性为95%。由于最后12个月的随访在试验期间缩短,因此12个月的数据丢失率很高,因此需要谨慎解释研究结果。然而,敏感性分析的范围支持基本情况的发现。结论:试验内经济评估发现,额外的物理治疗方案可能具有成本效益。然而,鉴于小而不精确的健康收益,鉴于目前对服务的其他需求,需要仔细考虑稀缺物理治疗资源的最佳利用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Bone & Joint Open
Bone & Joint Open ORTHOPEDICS-
CiteScore
5.10
自引率
0.00%
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0
审稿时长
8 weeks
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