Valério Silva de Carvalho, Lincoln Faria da Silva, Carlos Augusto Moreira de Sousa
{"title":"Distinguishing stroke from mimics in telemedicine: How well does the TM-Score perform in a Brazilian telestroke network?","authors":"Valério Silva de Carvalho, Lincoln Faria da Silva, Carlos Augusto Moreira de Sousa","doi":"10.1177/1357633X251334433","DOIUrl":null,"url":null,"abstract":"<p><p>BackgroundStroke is a leading cause of mortality and disability worldwide. In Brazil, ischemic strokes account for 85% of cases, but many hospitals lack resources for acute stroke care. Telestroke programs connect underserved hospitals to specialized centers, improving access to treatment. However, stroke mimics (SMs) pose a diagnostic challenge, potentially delaying appropriate management. The Telestroke Mimic Score (TM-Score) is a clinical tool designed to differentiate ischemic cerebrovascular disease (ICVD) from SM, but it has not been validated in South America. The objective of this study is to assess the validity of the TM-Score in distinguishing ICVD from SM in a Brazilian cohort.MethodsWe conducted a retrospective study using data from the Neurological Telemedicine Database of Hospital Pró-Cardíaco, Rio de Janeiro. Patients evaluated for suspected stroke via telemedicine (January 2019-December 2022) were classified as ICVD or SM by a telestroke neurologist. The TM-Score's performance was analyzed using receiver-operating characteristic (ROC) curves, sensitivity, specificity, and predictive values.ResultsAmong 777 patients (ICVD: 561, SM: 216), the mean TM-Score was significantly higher in ICVD (20.72 ± 6.86 vs 14.36 ± 5.73, <i>p</i> < 0.001). A score ≥25 had high specificity (96%) and PPV (95%) for ICVD, while <10 had an NPV of 0.71. The AUC was 0.755 (95% CI: 0.718-0.791).ConclusionThe TM-Score is a valuable tool for differentiating ICVD from SM in Brazil, supporting more accurate decision-making, particularly in telemedicine settings without stroke specialists.</p>","PeriodicalId":50024,"journal":{"name":"Journal of Telemedicine and Telecare","volume":" ","pages":"1357633X251334433"},"PeriodicalIF":3.2000,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Telemedicine and Telecare","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/1357633X251334433","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0
Abstract
BackgroundStroke is a leading cause of mortality and disability worldwide. In Brazil, ischemic strokes account for 85% of cases, but many hospitals lack resources for acute stroke care. Telestroke programs connect underserved hospitals to specialized centers, improving access to treatment. However, stroke mimics (SMs) pose a diagnostic challenge, potentially delaying appropriate management. The Telestroke Mimic Score (TM-Score) is a clinical tool designed to differentiate ischemic cerebrovascular disease (ICVD) from SM, but it has not been validated in South America. The objective of this study is to assess the validity of the TM-Score in distinguishing ICVD from SM in a Brazilian cohort.MethodsWe conducted a retrospective study using data from the Neurological Telemedicine Database of Hospital Pró-Cardíaco, Rio de Janeiro. Patients evaluated for suspected stroke via telemedicine (January 2019-December 2022) were classified as ICVD or SM by a telestroke neurologist. The TM-Score's performance was analyzed using receiver-operating characteristic (ROC) curves, sensitivity, specificity, and predictive values.ResultsAmong 777 patients (ICVD: 561, SM: 216), the mean TM-Score was significantly higher in ICVD (20.72 ± 6.86 vs 14.36 ± 5.73, p < 0.001). A score ≥25 had high specificity (96%) and PPV (95%) for ICVD, while <10 had an NPV of 0.71. The AUC was 0.755 (95% CI: 0.718-0.791).ConclusionThe TM-Score is a valuable tool for differentiating ICVD from SM in Brazil, supporting more accurate decision-making, particularly in telemedicine settings without stroke specialists.
期刊介绍:
Journal of Telemedicine and Telecare provides excellent peer reviewed coverage of developments in telemedicine and e-health and is now widely recognised as the leading journal in its field. Contributions from around the world provide a unique perspective on how different countries and health systems are using new technology in health care. Sections within the journal include technology updates, editorials, original articles, research tutorials, educational material, review articles and reports from various telemedicine organisations. A subscription to this journal will help you to stay up-to-date in this fast moving and growing area of medicine.