[Treatment with blood products in the intensive care unit].

IF 1.3 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Sirak Petros
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引用次数: 0

Abstract

The evidence for the administration of blood products in the critically ill is frequently meagre. It is often difficult to differentiate between adaptive changes and pathological alterations of blood components requiring treatment. Anemia is frequently observed in critically ill patients; however, there is no evidence for a benefit of a liberal transfusion strategy. Thrombocytopenia and alterations in plasmatic coagulation could correlate with an unfavorable outcome but they are not predictive regarding a substitution. Therefore, the indications for platelet transfusion and the administration of plasma or coagulation factor concentrates should always be clinically and critically evaluated. There is also no evidence for the generous use of albumin in intensive care medicine. In conclusion, a restrictive strategy is recommended for all blood products. The available evidence and a critical clinical assessment should be the mainstays of the decision for treatment with blood products.

[在重症监护室用血液制品治疗]。
在危重病人中使用血液制品的证据往往不足。通常很难区分需要治疗的血液成分的适应性改变和病理性改变。贫血常见于危重病人;然而,没有证据表明自由输血策略有好处。血小板减少和血浆凝血改变可能与不良结果相关,但它们不能预测替代。因此,血小板输注和血浆或凝血因子浓缩物的适应症应始终进行临床和批判性评估。也没有证据表明在重症监护医学中大量使用白蛋白。总之,建议对所有血液制品采取限制性策略。可用的证据和关键的临床评估应该是决定是否使用血液制品治疗的主要依据。
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来源期刊
CiteScore
2.60
自引率
9.10%
发文量
93
审稿时长
6-12 weeks
期刊介绍: Medizinische Klinik – Intensivmedizin und Notfallmedizin is an internationally respected interdisciplinary journal. It is intended for physicians, nurses, respiratory and physical therapists active in intensive care and accident/emergency units, but also for internists, anesthesiologists, surgeons, neurologists, and pediatricians with special interest in intensive care medicine. Comprehensive reviews describe the most recent advances in the field of internal medicine with special focus on intensive care problems. Freely submitted original articles present important studies in this discipline and promote scientific exchange, while articles in the category Photo essay feature interesting cases and aim at optimizing diagnostic and therapeutic strategies. In the rubric journal club well-respected experts comment on outstanding international publications. Review articles under the rubric "Continuing Medical Education" present verified results of scientific research and their integration into daily practice. The rubrics "Nursing practice" and "Physical therapy" round out the information.
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