Our experience with the localization of non-palpable breast lesions using the radioactive seed Advantage™ I-125.

Q4 Medicine
N Harciníková, K Jágrová, D Engelová, L Večeřová, Z Špůrková
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引用次数: 0

Abstract

Introduction: Non-palpable breast lesions that are eligible for breast-conserving surgery require precise preoperative localization of the pathological site. Mammographic screening and modern diagnostic methods contribute to the increasingly early detection of these lesions.

Methods: We present our two-year practical experience with the marking of non-palpa-ble breast lesions using the Advantage™ I-125 radioactive seed. This method was applied to 116 patients, 34 of whom had undergone successful neoadjuvant systemic therapy. The first 13 patients were marked using both the Frank wire method and radioactive seed application. The aim of our study was to evaluate the advantages and disadvantages of this method for both the patients and the entire multidisciplinary team.

Results: All pathological lesions were successfully removed during the primary procedure. In four patients, we observed seed displacement; however, the pathological lesion and the seed were always identified within the surgical field. Among the total number of patients, 73 underwent surgery for ductal carcinoma, 20 for lobular carcinoma, 8 for carcinoma associated with microcalcifications, 2 for invasive papillary carcinoma, and 13 for ambiguous biopsy findings. The method enables precise targeting of non-palpa-ble lesions with minimal radiation exposure for both the patients and the surgical team. Additionally, the cosmetic outcomes of this method were assessed as clearly positive.

Conclusion: The Advantage™ I-125 radioactive seed localization proved to be a reliable method for detecting non-palpable breast lesions with minimal complications. Its main advantages lie in the overall comfort for patients and the ability to optimize incision placement from an aesthetic perspective. Our results confirm the high effectiveness of this method in breast-conserving surgery while achieving R0 resection.

我们使用放射性种子Advantage™I-125定位不可触及乳腺病变的经验。
简介:符合保乳手术条件的不可触及的乳腺病变需要在术前精确定位病理部位。乳房x线摄影筛查和现代诊断方法有助于越来越早地发现这些病变。方法:我们介绍了我们使用Advantage™I-125放射性种子标记不可触摸乳房病变的两年实践经验。该方法应用于116例患者,其中34例成功接受了新辅助全身治疗。前13例患者采用弗兰克丝法和放射性种子应用进行标记。我们研究的目的是评估这种方法对患者和整个多学科团队的利弊。结果:所有病理病变均成功切除。在4例患者中,我们观察到种子移位;然而,病理病变和种子总是在手术视野内被识别。在所有患者中,73例导管癌,20例小叶癌,8例伴有微钙化的癌,2例浸润性乳头状癌,13例活检结果不明确。该方法使患者和手术团队能够以最小的辐射暴露精确定位不可触摸的病变。此外,该方法的美容效果被评估为明显阳性。结论:Advantage™I-125放射性粒子定位被证明是一种可靠的方法,用于检测不可触及的乳房病变,并发症最少。其主要优点在于患者的整体舒适度和从美学角度优化切口位置的能力。我们的结果证实了这种方法在实现R0切除的保乳手术中的高效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Rozhledy v Chirurgii
Rozhledy v Chirurgii Medicine-Medicine (all)
CiteScore
0.50
自引率
0.00%
发文量
67
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