New Perspectives on Non-Invasive Cerebellar Stimulation for Social and Affective Functions in Children and Adolescents.

IF 2.7 3区医学 Q3 NEUROSCIENCES

Cerebellum Pub Date : 2025-04-26 DOI:10.1007/s12311-025-01844-9

Ludovica Pasca, Romina Romaniello, Renato Borgatti, Andrea Ciricugno

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引用次数: 0

Abstract

Cerebellar dysfunction affects socio-affective abilities beyond motor control. Recent studies suggest that non-invasive cerebellar neurostimulation can modulate social cognition networks, offering potential therapeutic benefits for children with autism, ADHD, and mood disorders. However, its application in pediatrics remains largely unexplored. This review summarizes emerging pediatric research on cerebellar transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). We discuss their mechanisms, potential benefits, and safety considerations, highlighting preliminary findings that suggest feasibility and effectiveness. Ethical concerns and technical challenges related to pediatric neuroanatomy and stimulation parameters are also addressed. While early results are promising, further clinical trials and neurophysiological studies are essential to optimize protocols and confirm long-term efficacy. Advancing our understanding of cerebellar involvement in socio-affective functions could lead to innovative rehabilitation strategies for neurodevelopmental disorders.

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非侵入性小脑刺激对儿童和青少年社会和情感功能的新观点。

小脑功能障碍影响运动控制之外的社会情感能力。最近的研究表明，非侵入性的小脑神经刺激可以调节社会认知网络，为患有自闭症、多动症和情绪障碍的儿童提供潜在的治疗益处。然而，它在儿科的应用在很大程度上仍未被探索。本文综述了儿童小脑经颅磁刺激（TMS）和经颅直流刺激（tDCS）的最新研究进展。我们讨论了它们的机制、潜在的益处和安全性考虑，重点介绍了初步发现的可行性和有效性。与儿科神经解剖学和刺激参数相关的伦理问题和技术挑战也得到了解决。虽然早期结果很有希望，但进一步的临床试验和神经生理学研究对于优化方案和确认长期疗效至关重要。推进我们对小脑参与社会情感功能的理解可能会导致神经发育障碍的创新康复策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cerebellum 医学-神经科学

CiteScore

6.40

自引率

14.30%

发文量

150

审稿时长

4-8 weeks

期刊介绍： Official publication of the Society for Research on the Cerebellum devoted to genetics of cerebellar ataxias, role of cerebellum in motor control and cognitive function, and amid an ageing population, diseases associated with cerebellar dysfunction. The Cerebellum is a central source for the latest developments in fundamental neurosciences including molecular and cellular biology; behavioural neurosciences and neurochemistry; genetics; fundamental and clinical neurophysiology; neurology and neuropathology; cognition and neuroimaging. The Cerebellum benefits neuroscientists in molecular and cellular biology; neurophysiologists; researchers in neurotransmission; neurologists; radiologists; paediatricians; neuropsychologists; students of neurology and psychiatry and others.