{"title":"The Advanced Reasoning Capabilities of Large Language Models for Detecting Contraindicated Options in Medical Exams.","authors":"Yuichiro Yano, Mizuki Ohashi, Taiju Miyagami, Hirotake Mori, Yuji Nishizaki, Hiroyuki Daida, Toshio Naito","doi":"10.2196/68527","DOIUrl":null,"url":null,"abstract":"<p><strong>Unlabelled: </strong>Enhancing clinical reasoning and reducing diagnostic errors are essential in medical practice; OpenAI-o1, with advanced reasoning capabilities, performed better than GPT-4 on 15 Japanese National Medical Licensing Examination questions (accuracy: 100% vs 80%; contraindicated option detection: 87% vs 73%), though findings are preliminary due to the small sample size.</p>","PeriodicalId":56334,"journal":{"name":"JMIR Medical Informatics","volume":"13 ","pages":"e68527"},"PeriodicalIF":3.1000,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088613/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JMIR Medical Informatics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2196/68527","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICAL INFORMATICS","Score":null,"Total":0}
引用次数: 0
Abstract
Unlabelled: Enhancing clinical reasoning and reducing diagnostic errors are essential in medical practice; OpenAI-o1, with advanced reasoning capabilities, performed better than GPT-4 on 15 Japanese National Medical Licensing Examination questions (accuracy: 100% vs 80%; contraindicated option detection: 87% vs 73%), though findings are preliminary due to the small sample size.
期刊介绍:
JMIR Medical Informatics (JMI, ISSN 2291-9694) is a top-rated, tier A journal which focuses on clinical informatics, big data in health and health care, decision support for health professionals, electronic health records, ehealth infrastructures and implementation. It has a focus on applied, translational research, with a broad readership including clinicians, CIOs, engineers, industry and health informatics professionals.
Published by JMIR Publications, publisher of the Journal of Medical Internet Research (JMIR), the leading eHealth/mHealth journal (Impact Factor 2016: 5.175), JMIR Med Inform has a slightly different scope (emphasizing more on applications for clinicians and health professionals rather than consumers/citizens, which is the focus of JMIR), publishes even faster, and also allows papers which are more technical or more formative than what would be published in the Journal of Medical Internet Research.