Improving outcomes in electromagnetic navigation bronchoscopy-guided transbronchial microwave ablation for pulmonary nodules: the role of cone-beam computed tomography.
Yaochen Huang, Lin Zhou, Yongyong Wang, Jianing Wang, Zhipeng Hao, Xiangning Fu
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引用次数: 0
Abstract
Background: Studies have shown the potential of electromagnetic navigation bronchoscopy (ENB)-guided transbronchial microwave ablation (MWA) for treating pulmonary nodules. The role of cone-beam computed tomography (CBCT) in the procedure remains unknown.
Objectives: To investigate the efficacy and safety of employing CBCT during ENB-guided transbronchial MWA for pulmonary nodules.
Design: Retrospective analysis of clinical records.
Methods: Patients who underwent ENB-guided transbronchial MWA at the Department of Thoracic Surgery, Tongji Hospital. Patients were categorized into two groups: those who received CBCT during the procedure and those who did not. Technical and ablation success rates, complication rates, and patient characteristics were assessed.
Results: A total of 283 patients with 371 nodules were included in the final analysis. The technical success rate was significantly higher in the CBCT group (97.0%) compared to the non-CBCT group (91.5%, p = 0.034). The overall ablation success rate was 88.1%, with the CBCT group demonstrating a higher rate (90.9% vs 81.5%, p = 0.018). Complication rates were similar between the two groups, with no significant differences.
Conclusion: The use of CBCT in ENB-guided transbronchial MWA significantly increases the technical and ablation success rates without raising complication rates. These findings underscore the potential advantages of CBCT in enhancing procedural outcomes for patients with pulmonary nodules. Further validation through larger, multi-center studies with longer follow-up is warranted.
背景：研究显示电磁导航支气管镜（ENB）引导下的经支气管微波消融（MWA）治疗肺结节的潜力。锥束计算机断层扫描（CBCT）在手术中的作用尚不清楚。目的：探讨CBCT在enb引导下经支气管MWA治疗肺结节的有效性和安全性。设计：回顾性分析临床记录。方法：同济医院胸外科行enb引导下经支气管MWA的患者。患者被分为两组：在手术过程中接受CBCT的患者和未接受CBCT的患者。评估技术和消融成功率、并发症发生率和患者特征。结果：共纳入283例371个结节。CBCT组的技术成功率（97.0%）明显高于非CBCT组（91.5%,p = 0.034）。总体消融成功率为88.1%，CBCT组的消融成功率更高（90.9% vs 81.5%, p = 0.018）。两组并发症发生率相似，无显著差异。结论：CBCT在enb引导下经支气管MWA中的应用显著提高了技术成功率和消融成功率，且未增加并发症发生率。这些发现强调了CBCT在提高肺结节患者手术预后方面的潜在优势。有必要通过更大的、多中心的、更长的随访研究来进一步验证。
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Therapeutic Advances in Respiratory Disease delivers the highest quality peer-reviewed articles, reviews, and scholarly comment on pioneering efforts and innovative studies across all areas of respiratory disease.
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