{"title":"Efficacy of titanium-coated PEEK cages with two blades in anterior cervical decompression fixation: Bone fusion rates and surgical outcomes.","authors":"Taiki Hayashi, Shizumasa Murata, Hiroki Iwahashi, Hiroshi Hashizume, Hiroshi Iwasaki, Shunji Tsutsui, Masanari Takami, Keiji Nagata, Yuyu Ishimoto, Masatoshi Teraguchi, Yoshimasa Mera, Toshiya Shitahodo, Shingo Inoue, Kota Kawamura, Aozora Kadono, Kusushi Murai, Yoji Kitano, Hiroshi Yamada","doi":"10.1016/j.jos.2025.03.009","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Cervical degenerative diseases are prevalent in aging populations. Anterior cervical discectomy and fusion is a common surgical intervention. This study aimed to compare the efficacy of titanium-coated polyether ether ketone cages with blades and artificial bone grafting with that of conventional polyether ether ketone cages with screws and autologous bone grafting in anterior cervical discectomy and fusion.</p><p><strong>Methods: </strong>This retrospective study reviewed 61 patients who underwent anterior cervical discectomy and fusion for cervical spondylotic myelopathy at our institution. Patients were divided into two groups according to the treatment: polyether ether ketone cage with screws (Group S, n = 39) and titanium-coated polyether ether ketone cage with blades (Group B, n = 22). The primary outcome was the bone fusion rate at 6 months postoperatively. Secondary outcomes included operative time, intraoperative blood loss, retropharyngeal cavity width, wound pain, Japanese Orthopaedic Association scores, radiographic measurements, and cage subsidence.</p><p><strong>Results: </strong>The bone fusion rate was higher in Group B (93.3 %) than in Group S (78.7 %), albeit not significantly (p = 0.077). Group B had significantly shorter operative times (107.7 ± 27.3 vs. 139.9 ± 50.1 min, p = 0.007) and lower blood loss (21.4 ± 20.5 vs. 42.1 ± 35.7 mL, p = 0.016). Group B also experienced significantly lesser wound pain on postoperative day 3 (2.0 ± 1.0 vs. 3.0 ± 1.3, p = 0.002). The retropharyngeal cavity width at C5 was significantly smaller in Group B on days 3 (6.3 ± 1.9 vs. 7.6 ± 1.6 mm, p = 0.004) and 7 (5.2 ± 2.5 vs. 6.9 ± 2.9 mm, p = 0.025). No significant between-group differences were noted in the retropharyngeal cavity width at C7, Japanese Orthopaedic Association scores, radiographic measurements, or cage subsidence.</p><p><strong>Conclusion: </strong>Although the bone fusion rates were similar, the reduced surgical time and patient morbidity associated with graft harvesting suggest that titanium-coated polyether ether ketone cages with blades could improve patient care in anterior cervical discectomy and fusion.</p>","PeriodicalId":16939,"journal":{"name":"Journal of Orthopaedic Science","volume":" ","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Orthopaedic Science","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jos.2025.03.009","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Cervical degenerative diseases are prevalent in aging populations. Anterior cervical discectomy and fusion is a common surgical intervention. This study aimed to compare the efficacy of titanium-coated polyether ether ketone cages with blades and artificial bone grafting with that of conventional polyether ether ketone cages with screws and autologous bone grafting in anterior cervical discectomy and fusion.
Methods: This retrospective study reviewed 61 patients who underwent anterior cervical discectomy and fusion for cervical spondylotic myelopathy at our institution. Patients were divided into two groups according to the treatment: polyether ether ketone cage with screws (Group S, n = 39) and titanium-coated polyether ether ketone cage with blades (Group B, n = 22). The primary outcome was the bone fusion rate at 6 months postoperatively. Secondary outcomes included operative time, intraoperative blood loss, retropharyngeal cavity width, wound pain, Japanese Orthopaedic Association scores, radiographic measurements, and cage subsidence.
Results: The bone fusion rate was higher in Group B (93.3 %) than in Group S (78.7 %), albeit not significantly (p = 0.077). Group B had significantly shorter operative times (107.7 ± 27.3 vs. 139.9 ± 50.1 min, p = 0.007) and lower blood loss (21.4 ± 20.5 vs. 42.1 ± 35.7 mL, p = 0.016). Group B also experienced significantly lesser wound pain on postoperative day 3 (2.0 ± 1.0 vs. 3.0 ± 1.3, p = 0.002). The retropharyngeal cavity width at C5 was significantly smaller in Group B on days 3 (6.3 ± 1.9 vs. 7.6 ± 1.6 mm, p = 0.004) and 7 (5.2 ± 2.5 vs. 6.9 ± 2.9 mm, p = 0.025). No significant between-group differences were noted in the retropharyngeal cavity width at C7, Japanese Orthopaedic Association scores, radiographic measurements, or cage subsidence.
Conclusion: Although the bone fusion rates were similar, the reduced surgical time and patient morbidity associated with graft harvesting suggest that titanium-coated polyether ether ketone cages with blades could improve patient care in anterior cervical discectomy and fusion.
背景:宫颈退行性疾病在老年人群中普遍存在。颈前路椎间盘切除术和融合是一种常见的手术干预。本研究旨在比较钛包覆聚醚醚酮保持器刀片人工植骨与常规聚醚醚酮保持器螺钉自体植骨在颈前路椎间盘切除术融合中的疗效。方法:本回顾性研究回顾了61例在我院接受颈椎病前路椎间盘切除术和融合治疗的患者。根据治疗方法将患者分为螺钉聚醚醚酮笼(S组,n = 39)和刀片包钛聚醚醚酮笼(B组,n = 22)两组。主要观察指标为术后6个月的骨融合率。次要结果包括手术时间、术中出血量、咽后腔宽度、伤口疼痛、日本骨科协会评分、x线测量和手术笼下沉。结果:B组骨融合率(93.3%)高于S组(78.7%),但差异无统计学意义(p = 0.077)。B组手术时间明显缩短(107.7±27.3 vs 139.9±50.1 min, p = 0.007),出血量明显减少(21.4±20.5 vs 42.1±35.7 mL, p = 0.016)。B组术后第3天创面疼痛明显减轻(2.0±1.0比3.0±1.3,p = 0.002)。第3天(6.3±1.9 vs. 7.6±1.6 mm)和第7天(5.2±2.5 vs. 6.9±2.9 mm, p = 0.025), B组第5、7天咽后腔宽度明显小于对照组(p = 0.004)。在C7时咽后腔宽度、日本骨科协会评分、x线测量或笼下沉方面,组间无显著差异。结论:虽然骨融合率相似,但手术时间的缩短和移植物收获相关的患者发病率的降低表明钛包覆聚醚醚酮保持器与刀片可以改善颈椎前路椎间盘切除术和融合患者的护理。
期刊介绍:
The Journal of Orthopaedic Science is the official peer-reviewed journal of the Japanese Orthopaedic Association. The journal publishes the latest researches and topical debates in all fields of clinical and experimental orthopaedics, including musculoskeletal medicine, sports medicine, locomotive syndrome, trauma, paediatrics, oncology and biomaterials, as well as basic researches.