Do the Age of Children and Parental Status Matter in Valuing the Child Health Utility 9D (CHU9D)?

IF 4.4 3区 医学 Q1 ECONOMICS
PharmacoEconomics Pub Date : 2025-07-01 Epub Date: 2025-04-23 DOI:10.1007/s40273-025-01494-z
Xiuqin Xiong, Li Huang, Natalie Carvalho, Kim Dalziel, Nancy Devlin
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引用次数: 0

Abstract

Objectives: This study aims to test whether preferences for children's health states differ (a) when considering those aged 2-4 years compared with older children and (b) by parental status; we also aim to provide a value set that can be used for 2-4 years old.

Methods: Health states were described using the Child Health Utility 9D (CHU9D). A discrete choice experiment (DCE) survey was administered between September 2023 and March 2024 to a representative sample of the Australian general adult population which included a 20% quota of parents of 0-18-year-old children. Participants were randomly allocated to two study arms considering the health of a 2-4-year-old or a 10-year-old child. A conditional logit model was used to obtain the latent values from the choice responses. The differences in latent values between the two ages and between parental status were analyzed using relative attribute importance (RAI), poolability test, and pooled model with interaction terms. Visual Analogue Scale (VAS) responses were used to anchor the latent values onto a 0-1 utility scale.

Results: In all, 3112 participants were included. Results suggested that the preferences between the two age perspectives were similar, with only 1 out of 36 interaction terms being significant. Preferences of parents of children aged 0-18 years differed from those who were not, as indicated by three significant interaction terms and failure in poolability testing, having smaller disutility for severe health states in the Pain, Tired, and Joining in Activities dimensions.

Conclusion: In the valuation of CHU9D health states, asking respondents to consider a 2-4-year-old compared with a 10-year-old did not influence adults' preferences; however, the preferences of respondents who were parents of 0-18-year-olds at that time differed from those who were not. Two CHU9D value sets are reported for children 2 years and older, one derived from the general adult population and the other from parents.

儿童健康效用9D (CHU9D)的价值与儿童年龄和父母地位有关吗?
目的:本研究旨在测试儿童健康状态的偏好是否存在差异(a)当考虑2-4岁的儿童时,与年龄较大的儿童相比;(b)父母身份不同;我们还旨在提供一个价值集,可用于2-4岁。方法:使用儿童健康工具9D (CHU9D)描述健康状态。在2023年9月至2024年3月期间,对澳大利亚普通成年人的代表性样本进行了离散选择实验(DCE)调查,其中包括20%的0-18岁儿童的父母配额。考虑到2-4岁和10岁儿童的健康状况,参与者被随机分配到两个研究组。使用条件logit模型从选择回答中获得潜在值。采用相对属性重要度(relative attribute importance, RAI)、可poolability检验和带交互项的pooled模型分析不同年龄和父母身份之间的潜在值差异。使用视觉模拟量表(VAS)反应将潜在值固定在0-1的效用量表上。结果:共纳入3112名受试者。结果表明,两种年龄观点之间的偏好是相似的,36个相互作用项中只有1个是显著的。0-18岁儿童的父母的偏好不同于那些没有孩子的父母,正如三个显著的相互作用条件和poolability测试的失败所表明的那样,在疼痛、疲劳和参加活动维度中,严重健康状态的负效用较小。结论:在对幼儿健康状态的评价中,要求被调查者将2-4岁儿童与10岁儿童进行比较不影响成人的偏好;然而,当时有0-18岁孩子的父母的受访者的偏好与没有孩子的受访者有所不同。报告了2岁及以上儿童的两个CHU9D值集,一个来自一般成年人,另一个来自父母。
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来源期刊
PharmacoEconomics
PharmacoEconomics 医学-药学
CiteScore
8.10
自引率
9.10%
发文量
85
审稿时长
6-12 weeks
期刊介绍: PharmacoEconomics is the benchmark journal for peer-reviewed, authoritative and practical articles on the application of pharmacoeconomics and quality-of-life assessment to optimum drug therapy and health outcomes. An invaluable source of applied pharmacoeconomic original research and educational material for the healthcare decision maker. PharmacoEconomics is dedicated to the clear communication of complex pharmacoeconomic issues related to patient care and drug utilization. PharmacoEconomics offers a range of additional features designed to increase the visibility, readership and educational value of the journal’s content. Each article is accompanied by a Key Points summary, giving a time-efficient overview of the content to a wide readership. Articles may be accompanied by plain language summaries to assist readers who have some knowledge of, but not in-depth expertise in, the area to understand the scientific content and overall implications of the article.
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