Adham M Khalafallah, Nikola Susic, Khushi H Shah, Maxon V Knott, Chandler N Berke, Muhammet E Gurses, Victor M Lu, Michael E Ivan, Ricardo J Komotar, Ashish H Shah
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引用次数: 0
Abstract
Purpose: Laser interstitial thermal therapy (LITT) is a minimally invasive treatment for intracranial tumors. Enhanced recovery after surgery (ERAS) protocols aim to optimize patient outcomes, and same-day discharge (SDD) is an emerging strategy to improve efficiency while maintaining safety. This pilot study evaluates the feasibility and safety of SDD following LITT.
Methods: A retrospective review was conducted of patients who underwent LITT with planned SDD between May 2023 and June 2024 at our institution. Patients successfully discharged on the same day (study group) were match-paired 1:3 based on age, gender, and pathology, with patients discharged on post-ablation day 1 (control group) between January 2014 and April 2023. Demographic, perioperative, and treatment outcomes were compared.
Results: SDD was achieved in 10 patients (mean age 56.80 ± 11.43 years, 70% males), compared to 30 controls (mean age 58.87 ± 12.23, 70% males). SDD patients had a significantly shorter observation period (p < 0.001). No differences were observed in postoperative edema (p = 0.640), midline shift (p = 0.195), Karnofsky Performance Status (KPS) at follow-up (p = 0.999), 30-day postoperative complications (p = 0.620), 30-day neurosurgical complications (p = 0.999), 30-day readmission (p = 0.584), 30-day neurosurgical readmission (p = 0.999), or 90-day mortality (p = 0.999) between groups.
Conclusion: Our findings suggest that SDD following LITT is safe and feasible for appropriately selected patients. Rigorous patient selection and optimized perioperative protocols facilitate expedited recovery without compromising safety.
期刊介绍：
The Journal of Neuro-Oncology is a multi-disciplinary journal encompassing basic, applied, and clinical investigations in all research areas as they relate to cancer and the central nervous system. It provides a single forum for communication among neurologists, neurosurgeons, radiotherapists, medical oncologists, neuropathologists, neurodiagnosticians, and laboratory-based oncologists conducting relevant research. The Journal of Neuro-Oncology does not seek to isolate the field, but rather to focus the efforts of many disciplines in one publication through a format which pulls together these diverse interests. More than any other field of oncology, cancer of the central nervous system requires multi-disciplinary approaches. To alleviate having to scan dozens of journals of cell biology, pathology, laboratory and clinical endeavours, JNO is a periodical in which current, high-quality, relevant research in all aspects of neuro-oncology may be found.
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