The Synergistic Mechanisms and Prospects of Transarterial Chemoembolization Combined with Immunotherapy for Hepatocellular Carcinoma.

IF 4.2 3区 医学 Q2 ONCOLOGY
Journal of Hepatocellular Carcinoma Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI:10.2147/JHC.S514881
Qi-Feng Chen, Song Chen, Ming Zhao
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引用次数: 0

Abstract

Hepatocellular carcinoma (HCC) represents a highly aggressive form of liver neoplasm that presents various therapeutic obstacles. Recently, the synergistic use of transarterial chemoembolization (TACE) in conjunction with immunotherapy has attracted considerable interest within the medical community. This review aims to explore the synergistic mechanisms between TACE and immunotherapy, analyze the current research evidence, and discuss their potential applications in the treatment of HCC. By examining how TACE can enhance the efficacy of immunotherapy, we seek to provide direction for future research and emphasize the importance of personalized treatment strategies in managing HCC.

经动脉化疗栓塞联合免疫治疗肝癌的增效机制及展望。
肝细胞癌(HCC)是一种高度侵袭性的肝脏肿瘤,具有多种治疗障碍。最近,经动脉化疗栓塞(TACE)与免疫治疗的协同使用引起了医学界的极大兴趣。本文旨在探讨TACE与免疫治疗的协同作用机制,分析目前的研究证据,并讨论它们在HCC治疗中的潜在应用。通过研究TACE如何提高免疫治疗的疗效,我们寻求为未来的研究提供方向,并强调个性化治疗策略在HCC治疗中的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.50
自引率
2.40%
发文量
108
审稿时长
16 weeks
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